Publication year
2011Source
Bioorganic & Medicinal Chemistry Letters, 21, 12, (2011), pp. 3818-3822ISSN
Publication type
Article / Letter to editor

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Organization
Laboratory of Clinical Chemistry
Journal title
Bioorganic & Medicinal Chemistry Letters
Volume
vol. 21
Issue
iss. 12
Page start
p. 3818
Page end
p. 3822
Subject
N4i 4: Auto-immunity, transplantation and immunotherapyAbstract
MK2 kinase is a promising drug discovery target for the treatment of inflammatory diseases. Here, we describe the discovery of novel MK2 inhibitors using X-ray crystallography and structure-based drug design. The lead has in vivo efficacy in a short-term preclinical model.
This item appears in the following Collection(s)
- Academic publications [205104]
- Faculty of Medical Sciences [81055]
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