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Title: Selection of an M184V mutation in the cerebrospinal fluid of a treatment-naive HIV-infected individual starting darunavir-based therapy
Author(s): Cornelissen, M.; Back, N.K.; Burger, D.M. ; Blom, P.; Portegies, P.; Prins, J.M.; Valk, M. van der
Publication year: 2011
Source: Antiviral Therapy, vol. 16, iss. 6, (2011), pp. 931-935
ISSN: 1359-6535
DOI: https://doi.org/10.3851/IMP1781
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/97341   http://hdl.handle.net/2066/97341

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Subject: N4i 2: Invasive mycoses and compromised host
N4i 3: Poverty-related infectious diseases NCEBP 13: Infectious diseases and international health
Organization: Clinical Pharmacy
Ecological Microbiology
Journal title:
Antiviral Therapy
Volume: vol. 16
Issue: iss. 6
Page start: p. 931
Page end: p. 935
Abstract:
Here, we describe a newly diagnosed HIV-1-infected patient, in whom shortly after the initiation of a darunavir-based regimen, the HIV-1 virus exclusively mutated in the cerebrospinal fluid (CSF), leading to an increase in CSF HIV-1 RNA load and neurological complaints.

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