Selection of an M184V mutation in the cerebrospinal fluid of a treatment-naive HIV-infected individual starting darunavir-based therapy

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Publication year
2011Source
Antiviral Therapy, 16, 6, (2011), pp. 931-5ISSN
Publication type
Article / Letter to editor

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Organization
Clinical Pharmacy
Ecological Microbiology
Journal title
Antiviral Therapy
Volume
vol. 16
Issue
iss. 6
Page start
p. 931
Page end
p. 5
Subject
N4i 2: Invasive mycoses and compromised host; N4i 3: Poverty-related infectious diseases NCEBP 13: Infectious diseases and international healthAbstract
Here, we describe a newly diagnosed HIV-1-infected patient, in whom shortly after the initiation of a darunavir-based regimen, the HIV-1 virus exclusively mutated in the cerebrospinal fluid (CSF), leading to an increase in CSF HIV-1 RNA load and neurological complaints.
This item appears in the following Collection(s)
- Academic publications [227727]
- Electronic publications [107311]
- Faculty of Medical Sciences [86204]
- Faculty of Science [33769]
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