Habitual versus goal-directed action control in Parkinson disease
SourceJournal of Cognitive Neuroscience, 23, 5, (2011), pp. 1218-1229
Article / Letter to editor
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Journal of Cognitive Neuroscience
SubjectDCN 1: Perception and Action
This study presents the first direct investigation of the hypothesis that dopamine depletion of the dorsal striatum in mild Parkinson disease leads to impaired stimulus-response habit formation, thereby rendering behavior slow and effortful. However, using an instrumental conflict task, we show that patients are able to rely on direct stimulus-response associations when a goal-directed strategy causes response conflict, suggesting that habit formation is not impaired. If anything our results suggest a disease severity-dependent deficit in goal-directed behavior. These results are discussed in the context of Parkinson disease and the neurobiology of habitual and goal-directed behavior.
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