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Publication year
2011Source
International Journal of Gynecology & Obstetrics, 113, 2, (2011), pp. 96-99ISSN
Publication type
Article / Letter to editor

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Organization
Medical Microbiology
Gynaecology
Journal title
International Journal of Gynecology & Obstetrics
Volume
vol. 113
Issue
iss. 2
Page start
p. 96
Page end
p. 99
Subject
N4i 1: Pathogenesis and modulation of inflammation NCMLS 1: Infection and autoimmunity; ONCOL 1: Hereditary cancer and cancer-related syndromes; ONCOL 3: Translational research; ONCOL 5: Aetiology, screening and detection NCMLS 2: Immune Regulation; ONCOL 3: Translational researchAbstract
OBJECTIVE: To determine the prevalence of specific types of human papillomavirus (HPV), and the association with possible risk factors, among female university students at university in Honduras. METHODS: In a cross-sectional study, cervical samples from 400 women aged 18-35years were tested using a Roche HPV linear array to differentiate 37 genotypes of HPV. Associations with risk factors were assessed. RESULTS: Of the 400 participants, 393 completed the study. HPV DNA was detected in 45% of these women, of whom 73% were infected with high-risk types of HPV and 46% had multiple infections. Overall, 36 HPV genotypes were identified, of which HPV types 16, 51, 84, 66, and 39 were the most common. There was a marked decrease in the prevalence of multiple and high-risk infections with age. The factors that were independently associated with risk of being infected were related to sexual behavior and smoking habits. CONCLUSION: The study showed that genital HPV infection is common among sexually active women at university in Honduras. In addition, the Roche linear array was shown to be a valuable tool for HPV genotyping, which will be useful for monitoring the future effectiveness of an HPV vaccine in the population.
This item appears in the following Collection(s)
- Academic publications [202828]
- Electronic publications [100988]
- Faculty of Medical Sciences [80037]
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