Publication year
2011Source
Seminars in Fetal & Neonatal Medicine, 16, 3, (2011), pp. 139-144ISSN
Publication type
Article / Letter to editor

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Organization
Paediatrics
Journal title
Seminars in Fetal & Neonatal Medicine
Volume
vol. 16
Issue
iss. 3
Page start
p. 139
Page end
p. 144
Subject
IGMD 3: Genomic disorders and inherited multi-system disordersAbstract
The primary therapeutic target for congenital diaphragmatic hernia (CDH) patients has shifted from emergency surgical repair towards a non-operative emergency of the newborn treated by interdisciplinary teams. The increased understanding of the epidemiological and pathophysiological aspects of CDH have led to an improved knowledge and application of prenatal diagnosis, postnatal ventilation strategies, treatment of associated pulmonary hypertension and the role of extracorporeal membrane oxygenation therapy. In the surgical field, the perspectives have changed with delayed CDH repair, the introduction of minimally invasive surgery and use of prosthetic material for closure of large defects. With decreased mortality, long term multi-organ morbidity has increased in some survivors. In the near future, randomized controlled trials on different aspects of therapy will determine evidence-based optimal care.
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- Academic publications [204996]
- Faculty of Medical Sciences [81051]
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