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Publication year
2010Source
Psychotherapy and Psychosomatics, 79, 4, (2010), pp. 249-256ISSN
Annotation
1 juni 2010
Publication type
Article / Letter to editor

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Organization
Internal Medicine
Medical Oncology
Medical Psychology
Neurology
Journal title
Psychotherapy and Psychosomatics
Volume
vol. 79
Issue
iss. 4
Page start
p. 249
Page end
p. 256
Subject
N4i 1: Pathogenesis and modulation of inflammation; NCEBP 10: Human Movement & Fatigue; NCEBP 6: Quality of nursing and allied health care; NCEBP 8: Psychological determinants of chronic illness; NCEBP 8: Psychological determinants of chronic illnessAbstract
BACKGROUND: Cognitive behaviour therapy (CBT) for chronic fatigue syndrome (CFS) can decrease the level of fatigue and disabilities, but it has been suggested that during therapy some patients experience a deterioration of their symptoms rather than an improvement. The aim of this study is to examine the frequency and severity of symptom deterioration during CBT for CFS. METHODS: Data from 3 randomised controlled trials on CBT for CFS were pooled and reanalysed. Symptom deterioration during the trial was rated by patients and measured as deterioration in fatigue, pain, functional impairment and psychological distress. Both the frequency and severity of deterioration in these domains were compared between the patients receiving CBT and those in the control group. Predictors of symptom deterioration were identified by comparing their means in patients with and without an increase in fatigue. Statistically significant predictors were then combined in a logistic regression model. RESULTS: The frequency of symptom deterioration varied from 2 to 12% in patients receiving CBT and from 7 to 17% in the control group. None of the measures showed a significantly higher frequency of symptom deterioration in the CBT group. The severity of deterioration was also comparable in the CBT and in the control group. No predictors of symptom deterioration specific to CBT were found. CONCLUSION: Patients receiving CBT do not experience more frequent or more severe symptom deterioration than untreated patients. The reported deterioration during CBT seems to reflect the natural variation in symptoms. Thus, CBT is not only a helpful, but also a safe treatment for CFS.
This item appears in the following Collection(s)
- Academic publications [202801]
- Electronic publications [100942]
- Faculty of Medical Sciences [80020]
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