Spatial working memory in aging and mild cognitive impairment: Effects of task load and contextual cueing
until further notice
Number of pages
SourceNeuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition : a Journal on Normal and Dysfunctional Development, 17, 5, (2010), pp. 556-574
Article / Letter to editor
Display more detailsDisplay less details
SW OZ DCC NRP
PI Group Memory and Emotion
Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition : a Journal on Normal and Dysfunctional Development
Subject130 000 Cognitive Neurology & Memory; DCN 1: Perception and Action; DCN 2: Functional Neurogenomics; DCN 3: Neuroinformatics; DI-BCB_DCC_Theme 3: Plasticity and Memory; NCEBP 11: Alzheimer Centre; NCEBP 8: Psychological determinants of chronic illness; Neuropsychology and rehabilitation psychology; NCEBP 8: Psychological determinants of chronic illness; Neuro- en revalidatiepsychologie
Mild Cognitive Impairment (MCI) is characterized by episodic memory deficits, while aspects of working memory may also be implicated, but studies into this latter domain are scarce and results are inconclusive. Using a computerized search paradigm, this study compares 25 young adults, 25 typically aging older adults and 15 amnestic MCI patients as to their working-memory capacities for object-location information and potential differential effects of memory load and additional context cues. An age-related deficit in visuospatial working-memory maintenance was found that became more pronounced with increasing task demands. The MCI group additionally showed reduced maintenance of bound information, i.e., object-location associations, again especially at elevated memory load. No effects of contextual cueing were found. The current findings indicate that working memory should be considered when screening patients for suspected MCI and monitoring its progression.
Upload full text
Use your RU credentials (u/z-number and password) tolog in with SURFconextto upload a file for processing by the repository team.