Future of the TNM classification and staging system in head and neck cancer.
SourceHead and Neck-Journal for the Sciences and Specialties of the Head and Neck, 32, 12, (2010), pp. 1693-1711
1 december 2010
Article / Letter to editor
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Head and Neck-Journal for the Sciences and Specialties of the Head and Neck
SubjectONCOL 5: Aetiology, screening and detection
Staging systems for cancer, including the most universally used TNM classification system, have been based almost exclusively on anatomic information. However, the question arises whether staging systems should be based on this information alone. Other parameters have been identified that should be considered for inclusion in classification systems like the TNM. This is all the more important, as a shift toward nonsurgical treatments for head and neck cancer has been made over the years. For these treatment modalities tumor/biologic characteristics next to anatomic information may be particularly important for treatment choice and outcome. The shortcomings of the current TNM classification system will be discussed, along with suggestions for improvement and expansion of the TNM system based on tumor, patient, and environment-related factors. Further improvement of the TNM classification is expected to result in better treatment choices, outcome and prognostication of patients with head and neck cancer.
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