High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster.
Publication year
2010Source
Journal of Clinical Microbiology, 48, 9, (2010), pp. 3403-6ISSN
Annotation
01 september 2010
Publication type
Article / Letter to editor

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Organization
Medical Microbiology
Pulmonary Diseases
CMBI
Journal title
Journal of Clinical Microbiology
Volume
vol. 48
Issue
iss. 9
Page start
p. 3403
Page end
p. 6
Subject
N4i 3: Poverty-related infectious diseases; N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity; NCMLS 4: Energy and redox metabolismAbstract
To investigate whether genome sequencing yields more useful markers than those currently used to study the epidemiology of tuberculosis, it was applied to three Mycobacterium tuberculosis isolates of the Harlingen outbreak. Our findings suggest that single nucleotide polymorphisms can be used to identify transmission chains in restriction fragment length polymorphism clusters.
This item appears in the following Collection(s)
- Academic publications [227942]
- Electronic publications [107434]
- Faculty of Medical Sciences [86237]
- Open Access publications [76544]
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