
Fulltext:
88154thijssen.pdf
Embargo:
until further notice
Size:
601.0Kb
Format:
PDF
Description:
publisher's version
Publication year
2010Source
European Journal of Applied Physiology, 108, 5, (2010), pp. 845-75ISSN
Annotation
01 maart 2010
Publication type
Article / Letter to editor

Display more detailsDisplay less details
Organization
Physiology
Journal title
European Journal of Applied Physiology
Volume
vol. 108
Issue
iss. 5
Page start
p. 845
Page end
p. 75
Subject
IGMD 5: Health aging / healthy living; NCEBP 14: Cardiovascular diseasesAbstract
The effects of inactivity and exercise training on established and novel cardiovascular risk factors are relatively modest and do not account for the impact of inactivity and exercise on vascular risk. We examine evidence that inactivity and exercise have direct effects on both vasculature function and structure in humans. Physical deconditioning is associated with enhanced vasoconstrictor tone and has profound and rapid effects on arterial remodelling in both large and smaller arteries. Evidence for an effect of deconditioning on vasodilator function is less consistent. Studies of the impact of exercise training suggest that both functional and structural remodelling adaptations occur and that the magnitude and time-course of these changes depends upon training duration and intensity and the vessel beds involved. Inactivity and exercise have direct "vascular deconditioning and conditioning" effects which likely modify cardiovascular risk.
This item appears in the following Collection(s)
- Academic publications [227613]
- Electronic publications [107286]
- Faculty of Medical Sciences [86193]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.