Microevolution of Mycobacterium tuberculosis in a tuberculosis patient.
until further notice
SourceJournal of Clinical Microbiology, 48, 10, (2010), pp. 3813-3816
1 oktober 2010
Article / Letter to editor
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Journal of Clinical Microbiology
SubjectN4i 3: Poverty-related infectious diseases; N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity; N4i 3: Poverty-related infectious diseases NCMLS 1: Infection and autoimmunity
Five Mycobacterium tuberculosis isolates were obtained from three body sites from a Dutch patient. The isolates displayed a single genotype by 24-locus MIRU-VNTR typing (except for a single locus not amplified from one isolate) but were differentiated by small variations in IS6110 fingerprints, spoligotypes, 6 hypervariable MIRU-VNTR loci, and/or DiversiLab profiles, revealing patterns of microevolution in a clonal infection.
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