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Publication year
2010Source
European Journal of Pain, 14, 5, (2010), pp. 473.e1-9ISSN
Annotation
1 mei 2010
Publication type
Article / Letter to editor

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Organization
Anesthesiology
Anatomy
Journal title
European Journal of Pain
Volume
vol. 14
Issue
iss. 5
Page start
p. 473.e1
Page end
p. 9
Subject
DCN 1: Perception and Action; NCEBP 7: Effective primary care and public healthAbstract
Even in present day pain therapy, neuropathic pain remains a challenge for clinicians to treat and a challenge for researchers to investigate. Different animal models have been developed to mimic neuropathic pain. Neurotrophins such as nerve growth factor, brain-derived neurotrophic factor and neurotrophin 3 have been studied extensively in these models, yet few review articles concerning brain-derived neurotrophic factor have been published. This article reassesses the literature concerning brain-derived neurotrophic factor expression in the sciatic nerve chronic constriction injury model, the sciatic nerve transection model, the spinal nerve ligation model and the spinal nerve transection model and discusses differences in regulation of brain-derived neurotrophic factor between these models and their causality with neuropathic pain.
This item appears in the following Collection(s)
- Academic publications [205104]
- Electronic publications [103316]
- Faculty of Medical Sciences [81055]
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