Computational design, synthesis, and evaluation of miniproteins as androgen receptor coactivator mimics.
SourceChemical Communications, 2009, 36, (2009), pp. 5377-5379
Article / Letter to editor
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SubjectNCMLS 7: Chemical and physical biology
Insertion of 3 to 4 mutations, based on in silico modelling, in a diverse set of natural miniproteins generates potent androgen receptor (AR) binders and a clear insight into the structure-activity relationship of such coactivator mimics concerning helix length.
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