Six year survival after prolonged temozolomide treatment in a 30-year-old patient with glioblastoma.
Publication year
2009Source
Acta Neurologica Belgica, 109, 3, (2009), pp. 238-242ISSN
Publication type
Article / Letter to editor

Display more detailsDisplay less details
Organization
Pathology
Journal title
Acta Neurologica Belgica
Volume
vol. 109
Issue
iss. 3
Page start
p. 238
Page end
p. 242
Subject
NCMLS 3: Tissue engineering and pathology; ONCOL 3: Translational researchAbstract
Glioblastoma (GBM) is the most malignant primary brain tumour in adults. Since 2005 surgery followed by radiotherapy with concomitant Temozolomide (TMZ) is the standard care for patients with a GBM. Despite these improved treatment strategies, survival of GBM-patients remains poor; and there are very few patients who survive for a long time. Also there is no standard therapeutic strategy after six cycles of TMZ, and further treatment is at the physician's discretion. We report a case of a young patient with a glioblastoma who, not only showed dramatic clinical and radiological improvement after TMZ treatment but who now also (under continued TMZ therapy) survives over 6 years, with complete remission clinically and radiologically. Up till now there are no studies describing TMZ treatment in GBM patients for as long as 6 years.
This item appears in the following Collection(s)
- Academic publications [202828]
- Faculty of Medical Sciences [80037]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.