No evidence for long-term effectiveness of early osteodistraction in hemifacial microsomia.
until further notice
SourcePlastic and Reconstructive Surgery, 124, 6, (2009), pp. 2061-2071
Article / Letter to editor
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Plastic and Reconstructive Surgery
SubjectNCEBP 2: Evaluation of complex medical interventions
BACKGROUND: The authors performed a critical literature review to find evidence of the long-term stability after early distraction osteogenesis of the mandible in patients with hemifacial microsomia. METHODS: The PubMed, Cochrane, MEDLINE, EMBASE, CENTRAL, and CINAHL databases were searched systematically for studies performed between 2002 and 2008. Abstracts from the 89 relevant articles were reviewed for evidence. RESULTS: Thirteen articles met the inclusion criteria. Data were tabulated with respect to the length of follow-up, number of patients, age group, Pruzansky-Kaban classification of the patients, methods of analysis and validation, and level of evidence. Methods for long-term follow-up studies were not standardized, and no objective studies have been published on stability after growth cessation. CONCLUSIONS: Thus far, no randomized controlled trials on early distraction osteogenesis in hemifacial microsomia patients have been published. The authors conclude that there is a lack of statistical evidence to support the use of early distraction osteogenesis for correcting hemifacial microsomia as a single treatment modality. The results call into question its rationale.
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