Treatment of knee prosthesis infections: evaluation of 15 patients over a 5-year period.
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Publication year
2009Source
International Orthopaedics, 33, 5, (2009), pp. 1249-54ISSN
Publication type
Article / Letter to editor
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Organization
Internal Medicine
Medical Microbiology
Orthopaedics
Journal title
International Orthopaedics
Volume
vol. 33
Issue
iss. 5
Page start
p. 1249
Page end
p. 54
Subject
N4i 1: Pathogenesis and modulation of inflammation; N4i 2: Invasive mycoses and compromised host; NCEBP 10: Human Movement & Fatigue; NCEBP 13: Infectious diseases and international health; NCMLS 1: Infection and autoimmunityAbstract
Our objective was to evaluate different treatment alternatives for total knee arthroplasty (TKA) infection and to compare outcomes depending on adherence to a current treatment algorithm. All patients treated for a first episode of TKA infection between January 2000 and July 2005 were included. Patient records were reviewed and data were extracted retrospectively. Fifteen patients were followed up for a median of 25 months. The cure rate in patients with two-stage exchange of knee prosthesis was higher than in patients who had debridement without implant removal (100 vs 37%, p = 0.03). Cure rates were not different between these two surgical approaches in ten patients who were treated according to a current treatment algorithm. Success rates for treatment of TKA infections varied considerably with the treatment strategy chosen. Our results support the use of existing algorithms to select patients who are eligible for debridement with retention of the prosthesis or need two-stage exchange of knee implants.
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- Faculty of Medical Sciences [93208]
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