Apathy and depressive mood in nursing home patients with early-onset dementia.

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Title:	Apathy and depressive mood in nursing home patients with early-onset dementia.
Author(s):	Leontjevas, R. ; Hooren, S.A.H. van; Waterink, W.; Mulders, A.
Publication year:	2009
Source:	American Journal of Alzheimer's Disease and Other Dementias, vol. 24, iss. 4, (2009), pp. 341-348
ISSN:	1533-3175
DOI:	https://doi.org/10.1177/1533317509333905
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/80146
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Subject:	NCEBP 7: Effective primary care and public health
Organization:	Primary and Community Care
Journal title:	American Journal of Alzheimer's Disease and Other Dementias
Volume:	vol. 24
Issue:	iss. 4
Page start:	p. 341
Page end:	p. 348
Abstract:	The study explored whether apathy and depressive mood symptoms (DMS) are related to cognitive and functional features of dementia in 63 nursing home (NH) residents with early-onset dementia (EOD). All EOD residents from one NH (n = 41) and a random sample from another NH were assessed for depressive symptoms (Montgomery Asberg Depression Rating Scale [MADRS]), apathy (Neuropsychiatric Inventory [NPI]), global cognitive functions (Mini-Mental State Examination [MMSE]), activities of daily living (ADL, Minimum Data Set-Resident Assessment Instrument [MDS-RAI]), and overall dementia severity (Global Deterioration Scale [GDS]). DMS were not associated with apathy and dementia severity. Regression analyses adjusted for age, gender, the type of dementia, and DMS revealed that dementia severity measures accounted, respectively, for 14% (ADL), 13% (GDS), and 9% (MMSE) of the variance in apathy. In line with previous research in older patients, the higher apathy scores were associated with more cognitive and functional problems in EOD.