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Publication year
2009Source
Value in Health, 12, 4, (2009), pp. 466-72ISSN
Publication type
Article / Letter to editor

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Organization
IQ Healthcare
Health Evidence
Former Organization
Centre for Quality of Care Research
Epidemiology, Biostatistics & HTA
Journal title
Value in Health
Volume
vol. 12
Issue
iss. 4
Page start
p. 466
Page end
p. 72
Subject
NCEBP 2: Evaluation of complex medical interventions; NCEBP 3: Implementation Science; ONCOL 1: Hereditary cancer and cancer-related syndromes; ONCOL 4: Quality of Care; ONCOL 5: Aetiology, screening and detectionAbstract
Childhood urinary tract infections (UTIs) can lead to renal scarring and ultimately to terminal renal failure, which has a high impact on quality of life, survival, and health-care costs. Variation in the treatment of UTIs between practices is high. OBJECTIVE: To assess the cost-effectiveness of a maximum care model for UTIs in children, implying more testing and antibiotic treatment, compared with current practice in primary care in The Netherlands. METHODS: We performed a probabilistic modeling study using Markov models. Figures used in the model were derived from a systematic review of the research literature. Multidimensional Monte Carlo simulation was used for the probabilistic analyses. RESULTS: Maximum care gained 0.00102 (males) and 0.00219 (girls) QALYs (quality-adjusted life-years) and saved 42.70 euro (boys) and 77.81 euro (girls) in 30 years compared with current care, and was thus dominant. Net monetary benefit of maximum care ranged from 20 euro to 200 euro for a willingness to pay for a QALY ranging from 0 euro to 80,000 euro, respectively. Maximum care was also dominant over improved current care, although less dominant than to current care. CONCLUSIONS: This study suggested that maximum care for childhood UTI was dominant in the long run to current care, meaning that it delivered more quality of life at lower costs. Nevertheless, making firm conclusions is not possible, given the limitations of the input data.
This item appears in the following Collection(s)
- Academic publications [227437]
- Electronic publications [107154]
- Faculty of Medical Sciences [86157]
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