[Target-controlled infusion. Clinical relevance and special features when using pharmacokinetic models]
until further notice
SourceAnaesthesist, 58, 7, (2009), pp. 708-715
Article / Letter to editor
Display more detailsDisplay less details
SubjectDCN 1: Perception and Action
Since its commercial introduction in 1996, target-controlled infusion (TCI) has become an established technique for administration of intravenous anaesthetics. Modern TCI systems, however, are characterized by an increasing number of additional options and features, such as the choice between different pharmacokinetic models and modes of application, which may confuse the less experienced user. This review describes the differences between pharmacokinetic models, modes of application and the effect of covariates as well as the consequences for dosing. The aim is to explicate for the user of modern TCI systems the underlying scientific concepts and the relevance for clinical practice.
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.