[Sugammadex. New pharmacological concept for antagonizing rocuronium and vecuronium]
until further notice
SourceAnaesthesist, 58, 1, (2009), pp. 66-80
Article / Letter to editor
Display more detailsDisplay less details
SubjectDCN 1: Perception and Action
Up to now only acetylcholine esterase inhibitors, such as neostigmine, were available as antagonists of residual neuromuscular blocks. Sugammadex is a modified gamma-cyclodextrin that binds rocuronium and chemically similar aminosteroidal muscle relaxants, such as vecuronium. The underlying mechanism of action is new and differs completely from that of acetylcholine esterase inhibitors. This review summarizes data published so far within the framework of the licensing procedure about the efficacy, safety and side-effects of sugammadex and presents potential new anesthesiological concepts using this compound.
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.