until further notice
SourceEuropean Heart Journal, 29, 21, (2008), pp. 2681-8
Article / Letter to editor
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Cardio Thoracic Surgery
Paediatrics - OUD tm 2017
European Heart Journal
SubjectDCN 1: Perception and Action; DCN 2: Functional Neurogenomics; EBP 1: Determinants of Health and Disease; IGMD 1: Functional imaging; NCEBP 8: Psychological determinants of chronic illness; UMCN 3.1: Neuromuscular development and genetic disorders; UMCN 3.2: Cognitive neurosciences; UMCN 5.5: Nutrition and Health
AIMS: Although neurocognitive problems after open-heart surgery for congenital heart disease are frequent, due to a shortage of prospective studies assessing neurocognitive functioning both before and after the procedure, the exact nature of the deficits usually remains unknown. The present study aims at assessing the neurocognitive effects of, in particular, cardiopulmonary bypass at school age. In addition, surgery-related risk factors for reduced neurocognitive outcome are explored. METHODS AND RESULTS: Participants were aged between 6 and 16 years. Forty-three children indicated for open-heart surgery and a comparison group of 19 children scheduled for interventional cardiac catheterization completed a neurocognitive assessment battery before and 1 year after their procedures. Forty healthy matched controls did so at a 1 year interval. The baseline-to-follow-up outcomes were similar in all three groups. The observed improvements most likely resulted from increased age and the repeated neurocognitive assessment. No risk factors for postsurgical neurocognitive deficits were identified. CONCLUSION: The present study demonstrates that at school age cardiac surgery using full-flow cardiopulmonary bypass does not affect neurocognitive functioning.
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