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Title: Reproductive disorders among male and female greenhouse workers.
Author(s): Bretveld, R.W. ; Hooiveld, M. ; Zielhuis, G.A. ; Pellegrino, A. ; Rooij, I.A.L.M. van ; Roeleveld, N.
Publication year: 2008
Source: Reproductive Toxicology, vol. 25, iss. 1, (2008), pp. 107-114
ISSN: 0890-6238
DOI: http://dx.doi.org/10.1016/j.reprotox.2007.08.005
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/71185   https://hdl.handle.net/2066/71185

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Subject: IGMD 3: Genomic disorders and inherited multi-system disorders
NCEBP 12: Human Reproduction
NCEBP 2: Evaluation of complex medical interventions
ONCOL 2: Age-related aspects of cancer
UMCN 5.2: Endocrinology and reproduction
Organization: Health Evidence
Primary and Community Care
Former Organization: Epidemiology, Biostatistics & HTA
Journal title:
Reproductive Toxicology
Volume: vol. 25
Issue: iss. 1
Page start: p. 107
Page end: p. 114
Abstract:
The aim of this study was to evaluate reproductive disorders in male and female greenhouse workers. In 2002, data were collected from 4872 Dutch greenhouse workers and 8133 referents through postal questionnaires with detailed questions on reproductive disorders of the most recent pregnancy, lifestyle habits, and occupational exposures (e.g. pesticides) prior to conception. Different reproductive outcome measures were compared between 957 male and 101 female greenhouse workers and 1408 referents by means of logistic regression analyses. The analyses of primigravidous couples showed a slightly elevated risk of prolonged TTP (OR(women)=1.9; 95% CI: 0.8-4.4) and an increased risk of spontaneous abortion among female greenhouse workers (OR(women)=4.0; 95% CI: 1.1-14.0). A decreased risk of preterm birth was found among male greenhouse workers (OR(men)=0.1; 95% CI: 0.03-0.5). This study may offer some evidence for the hypothesis that pesticide exposure affects human reproduction leading to spontaneous abortion and possibly to prolonged time-to-pregnancy.

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