Publication year
2008Source
International Journal of Std & Aids, 19, 10, (2008), pp. 668-675ISSN
Publication type
Article / Letter to editor

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Organization
Radboudumc Extern
Paediatrics
Journal title
International Journal of Std & Aids
Volume
vol. 19
Issue
iss. 10
Page start
p. 668
Page end
p. 675
Subject
N4i 1: Pathogenesis and modulation of inflammation; N4i 3: Poverty-related infectious diseases; N4i 4: Auto-immunity, transplantation and immunotherapy; UMCN 4.1: Microbial pathogenesis and host defenseAbstract
This paper provides an estimation of the lifetime health-care cost of HIV-infected children and an update of the cost-effectiveness of universal HIV-screening of pregnant women in Amsterdam (The Netherlands). During 2003-2005, we collected data concerning the prevalence of newly diagnosed HIV-infected pregnant women in Amsterdam. Also, data on resource utilization and HAART regimen for HIV-infected children was gathered from a national registry. Using Kaplan-Meier survival analysis, we estimated the life-expectancy of a vertically HIV-infected child at 19 years, with the corresponding lifetime health-care costs of 179,974 Euros. HIV-screening of pregnant women could prevent 2.4 HIV transmissions annually in Amsterdam, based on an estimated prevalence of nine yet undiagnosed HIV-positive pregnant women per 10,000 pregnancies. We show that universal HIV screening during pregnancy generates significant net cost savings and health benefits in most situations. Universal antenatal HIV screening is justified in Amsterdam from a health-economic point of view.
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- Academic publications [204968]
- Faculty of Medical Sciences [81049]
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