Divided within: heterogeneity within adult stem cell pools.
SourceCell, 135, 6, (2008), pp. 1006-1008
Article / Letter to editor
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SubjectUMCN 1.2: Molecular diagnosis, prognosis and monitoring; UMCN 1.4: Immunotherapy, gene therapy and transplantation; UMCN 1.4: Immunotherapy, gene therapy and transplantation
In this issue, Wilson et al. (2008) demonstrate that there are two functional subsets of hematopoietic stem cells that have distinctive kinetics of cell cycling. They present evidence that cells may transition between the two kinetic states, establishing one subpopulation that is ready to proliferate and another that is a deeply quiescent reserve.
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