Electron tomography shows molecular anchoring within a layer-by-layer film.
until further notice
Number of pages
SourceJournal of the American Chemical Society, 130, 38, (2008), pp. 12608-12609
Article / Letter to editor
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Periodontology and Biomaterials
Physical Organic Chemistry
Synthetic Organic Chemistry
Physical Organic and Supramolecular Chemistry
Journal of the American Chemical Society
SubjectNCMLS 1: Immunity, infection and tissue repair; NCMLS 3: Tissue engineering and pathology; NCMLS 7: Chemical and physical biology; Physical Organic Chemistry
The layer-by-layer self-assembly of thin films consisting of alternating layers of DNA and bis-urea nanoribbons prevents diffusion of the components within the film and allows the anchoring of biotinylated molecules through molecular recognition in a predetermined layer of the film. Electron tomography demonstrates with nanometer precision the location of gold-labeled streptavidin bound to the incorporated biotinylated molecules.
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