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Publication year
2008Source
Pediatric Nephrology, 23, 2, (2008), pp. 307-10ISSN
Publication type
Article / Letter to editor
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Organization
Paediatrics - OUD tm 2017
Neurology
Journal title
Pediatric Nephrology
Volume
vol. 23
Issue
iss. 2
Page start
p. 307
Page end
p. 10
Subject
IGMD 5: Health aging / healthy living; IGMD 8: Mitochondrial medicine; UMCN 3.2: Cognitive neurosciences; UMCN 5.2: Endocrinology and reproductionAbstract
Juvenile cystinosis was diagnosed in a patient who presented with severe headache attacks and photophobia. Treatment with oral cysteamine and topical cysteamine eye drops was started. One-and-a-half years later, he developed unilateral gynecomastia and elevated prolactin and growth hormone levels. A pituitary macroprolactinoma was discovered and successfully treated with the dopamine agonist cabergoline. Increased serum growth hormone levels were attributed to enhanced growth hormone production by the prolactinoma and somatostatin inhibition by cysteamine. Although the occurrence of prolactinoma in this patient could be a simple coincidence, it might also be a rare yet unrecognised complication of cystinosis.
This item appears in the following Collection(s)
- Academic publications [245410]
- Electronic publications [132943]
- Faculty of Medical Sciences [93205]
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