Guided self-instructions for people with chronic fatigue syndrome: randomised controlled trial.
until further notice
SourceBritish Journal of Psychiatry, 193, 4, (2008), pp. 340-341
Article / Letter to editor
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British Journal of Psychiatry
SubjectEBP 1: Determinants of Health and Disease; EBP 3: Effective Primary Care and Public Health; N4i 1: Pathogenesis and modulation of inflammation; N4i 2: Invasive mycoses and compromised host; NCEBP 10: Human Movement & Fatigue; NCMLS 1: Infection and autoimmunity; ONCOL 4: Quality of Care; UMCN 4.1: Microbial pathogenesis and host defense; EBP 1: Determinants of Health and Disease; NCEBP 10: Human Movement & Fatigue
A minimal intervention, based on cognitive-behavioural therapy for chronic fatigue syndrome and consisting of self-instructions combined with email contact, was tested in a randomised controlled trial (ISRCTN27293439). A total of 171 patients participated in the trial: 85 were allocated to the intervention condition and 86 to the waiting-list condition. All patients met the Centers for Disease Control and Prevention criteria for chronic fatigue syndrome. An intention-to-treat analysis showed a significant decrease in fatigue and disability after self-instruction. The level of disability was negatively correlated with treatment outcome. Guided self-instructions are an effective treatment for patients with relatively less severe chronic fatigue syndrome.
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