A place for SSRIs in the treatment of severely depressed children and adolescents

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Title:	A place for SSRIs in the treatment of severely depressed children and adolescents
Author(s):	Roobol, T.H.; Buitelaar, J.K.
Publication year:	2008
Source:	Nederlands Tijdschrift voor Geneeskunde, vol. 152, iss. 31, (2008), pp. 1710-1712
ISSN:	0028-2162
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/69360
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Subject:	110 012 Social cognition of verbal communication DCN 1: Perception and Action DCN 3: Neuroinformatics EBP 1: Determinants in Health and Disease NCEBP 9: Mental health UMCN 3.2: Cognitive neurosciences
Organization:	Psychiatry PI Group MR Techniques in Brain Function
Former Organization:	F.C. Donders Centre for Cognitive Neuroimaging
Journal title:	Nederlands Tijdschrift voor Geneeskunde
Volume:	vol. 152
Issue:	iss. 31
Page start:	p. 1710
Page end:	p. 1712
Abstract:	Although in the past there were objections against the use of selective serotonin reuptake inhibitors (SSRIs) for the treatment of depression in children and adolescents, recent studies have shown that SSRIs, in particular fluoxetine, are effective against depression in this age group. Cognitive behavioural therapy has a questionable effect in children and adolescents with severe depression. Other unequivocally effective treatment options are not available. More suicidal behaviour was reported in children and adolescents using sertraline or venlafaxine, but fluoxetine did not clearly enhance this behaviour. Children with severe depression or a depression not responding to psychological therapy can be treated with SSRIs. Fluoxetine is the treatment of first choice.