Predictors of efficacy in depression prevention programmes. Meta-analysis.

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Title:	Predictors of efficacy in depression prevention programmes. Meta-analysis.
Author(s):	Jané Llopis, E. ; Hosman, C.M.H. ; Jenkins, R.B.; Anderson, P.D.
Publication year:	2003
Source:	British Journal of Psychiatry, vol. 183, iss. 5, (2003), pp. 384-397
ISSN:	0007-1250
DOI:	http://dx.doi.org/10.1192/bjp.183.5.384
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : http://hdl.handle.net/2066/63159
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Subject:	EBP 4: Quality of Care
Organization:	IQ Healthcare SW OZ BSI KLP
Former Organization:	Centre for Quality of Care Research
Journal title:	British Journal of Psychiatry
Volume:	vol. 183
Issue:	iss. 5
Page start:	p. 384
Page end:	p. 397
Abstract:	BACKGROUND: Worldwide, 340 million people are affected by depression, with high comorbid, social and economic costs. AIMS: To identify potential predictors of effect in prevention programmes. METHOD: A meta-analysis was made of 69 programmes to reduce depression or depressive symptoms. RESULTS: The weighted mean effect size of 0.22 was effective for different age groups and different levels of risk, and in reducing risk factors and depressive or psychiatric symptoms. Programmes with larger effect sizes were multi-component, included competence techniques, had more than eight sessions, had sessions 60-90 min long, had a high quality of research design and were delivered by a health care provider in targeted programmes. Older people benefited from social support, whereas behavioural methods were detrimental. CONCLUSIONS: An 11% improvement in depressive symptoms can be achieved through prevention programmes. Single trial evaluations should ensure high quality of the research design and detailed reporting of results and potential predictors.