Caries-inhibiting effect of professional fluoride gel application in low-caries children initially aged 4.5-6.5 years.

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Title:	Caries-inhibiting effect of professional fluoride gel application in low-caries children initially aged 4.5-6.5 years.
Author(s):	Rijkom, H.M. van; Truin, G.J. ; Hof, M.A. van 't
Publication year:	2004
Source:	Caries Research, vol. 38, iss. 2, (2004), pp. 115-123
ISSN:	0008-6568
DOI:	https://doi.org/10.1159/000075935
Publication type:	Article / Letter to editor
Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/58720
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Subject:	EBP 3: Effective Primary Care and Public Health
Organization:	Preventative Restorative Dentistry
Journal title:	Caries Research
Volume:	vol. 38
Issue:	iss. 2
Page start:	p. 115
Page end:	p. 123
Abstract:	It was the purpose of the study to investigate the caries-reducing effect of semi-annual professional fluoride gel application in a low-caries child population initially aged 4.5-6.5 years during a 4-year follow-up period. In a double-blind randomised controlled trial (n = 773) the effect of sodium fluoride gel on D3MFS and d3mfs was compared with a placebo gel. The mean caries reduction of professionally applied fluoride gel after 4 years in subjects with baseline caries experience D3MFS = 0 as well as d3mfs = 0 was 0.08 D3MFS (SE = 0.06) and 0.36 d3mfs (SE = 0.22). The prevented fraction for D3MFS and d3mfs was 26% (SE = 16%) and 20% (SE = 11%), respectively. It was concluded that in the investigated low-caries 4.5- to 6.5-year-olds, fluoride gel treatment showed a statistically significant (tested one-sided) caries-inhibiting effect on D3MFS, which was considered not clinically relevant, and no significant effect on d3mfs.