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Title: Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats.
Author(s): Fennis, J.P.M. ; Stoelinga, P.J.W. ; Jansen, J.A.
Publication year: 2004
Source: International Journal of Oral and Maxillofacial Surgery, vol. 33, iss. 1, (2004), pp. 48-55
ISSN: 0901-5027
DOI: https://doi.org/10.1054/ijom.2003.0452
Publication type: Article / Letter to editor

Please use this identifier to cite or link to this item : https://hdl.handle.net/2066/57151   https://hdl.handle.net/2066/57151

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Subject: UMCN 4.3: Tissue engineering and reconstructive surgery
Organization: Oral and Maxillofacial Surgery
Periodontology and Biomaterials
Journal title:
International Journal of Oral and Maxillofacial Surgery
Volume: vol. 33
Issue: iss. 1
Page start: p. 48
Page end: p. 55
Abstract:
Twenty-eight goats underwent a continuity resection of the mandibular angle. In all goats primary reconstruction was carried out using specially designed pre-shaped osteosynthesis plates and monocortical screws. The original cortical scaffold was used to bridge the defect, filled with an autogenous particulate bone graft in 14 goats, whereas platelet-rich-plasma (PRP) was added in another 14 goats. Both groups were divided in three subgroups that were sacrificed after 3, 6 and 12 weeks. Histological and histomorphometric evaluation revealed that the use of PRP enhanced the bone healing considerably. This effect was statistically significant and particularly visible in the 6 and 12 weeks' groups

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