Maintaining the nelfinavir trough concentration above 0.8 mg/L improves virologic response in HIV-1-infected children.
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Publication year
2004Source
Journal of Pediatrics, 145, 3, (2004), pp. 403-5ISSN
Publication type
Article / Letter to editor
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Organization
Clinical Pharmacy
Paediatrics - OUD tm 2017
Journal title
Journal of Pediatrics
Volume
vol. 145
Issue
iss. 3
Page start
p. 403
Page end
p. 5
Subject
UMCN 4.1: Microbial pathogenesis and host defenseAbstract
Differences in virologic response were compared in 32 HIV-infected children with a nelfinavir trough concentration either below (n=7) or above (n=25) 0.8 mg/L. Virologic response at week 48 was observed in 29% of children with subtherapeutic nelfinavir troughs versus 80% in children with therapeutic nelfinavir troughs (P=.02).
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- Faculty of Medical Sciences [92874]
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