[Treatment of intestinal failure in adults. II. Pharmacological treatment options]
until further notice
SourceNederlands Tijdschrift voor Geneeskunde, 151, 33, (2007), pp. 1825-1828
Article / Letter to editor
Display more detailsDisplay less details
Nederlands Tijdschrift voor Geneeskunde
SubjectIGMD 2: Molecular gastro-enterology and hepatology; UMCN 5.5: Nutrition and Health
For patients with severe intestinal failure caused by short-bowel syndrome, pharmacological treatment options are available that can reduce the period in which parenteral nutrition is required. Appropriate agents include acid inhibitors, bile-salt binders, inhibitors of motility and secretion, antibiotics and pre- and probiotics. A number of intestinotrophic factors have also been identified that are reported to enhance the functional adaptation of the intestine following surgery or illness. These include glutamine, growth hormone, and glucagon-like peptide 2 and its analogues. Absorption of certain agents is reduced when specific portions of the intestine are lacking. For example, fat-soluble cyclosporine is poorly resorbed in patients without an ileum.
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.