Multiple complications due to osteoradionecrosis in a patient with thromboangiitis obliterans.
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SourceOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 104, 1, (2007), pp. e34-7
Article / Letter to editor
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Oral and Maxillofacial Surgery
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
SubjectNCEBP 2: Evaluation of complex medical interventions; UMCN 1.2: Molecular diagnosis, prognosis and monitoring; UMCN 1.5: Interventional oncology; UMCN 4.3: Tissue engineering and reconstructive surgery
A case is presented of a patient with thromboangiitis obliterans (TAO) who developed severe necrosis of the intraoral soft tissues and maxillary and mandibular bone after radiotherapy for a cT2N0M0 squamous cell carcinoma of the soft palate. Multiple surgical procedures including partial resection of the mandible and maxilla and reconstruction of intraoral and extraoral defects with a pectoralis major myocutaneous flap and anterolateral thigh flap were performed with partial success. Although a causal relationship between TAO and the described complications cannot be verified, close monitoring of patients with TAO who are being treated with radiotherapy is advised.
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