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Publication year
2007Source
Neuromuscular Disorders, 17, 7, (2007), pp. 509-16ISSN
Publication type
Article / Letter to editor

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Organization
Neurology
Paediatrics - OUD tm 2017
Journal title
Neuromuscular Disorders
Volume
vol. 17
Issue
iss. 7
Page start
p. 509
Page end
p. 16
Subject
DCN 1: Perception and Action; DCN 2: Functional Neurogenomics; UMCN 3.1: Neuromuscular development and genetic disordersAbstract
In this study we investigated the diagnostic value of quantitative skeletal muscle ultrasonography in 150 consecutively referred children with symptoms suspect for a neuromuscular disorder. Muscle thickness and quantitatively determined echo intensity of four muscles and the distribution of these variables within the body were examined. RESULTS: Patients with and without a neuromuscular disorder could be discriminated with a positive predictive value of 91% and a negative predictive value of 86%. Patients with a neurogenic disorder could be distinguished from myopathies and non-neuromuscular disorders with a positive predictive value of 86% and a negative predictive of 84%, using the pattern of distribution of pathology within the body. CONCLUSIONS: Skeletal muscle ultrasound is a good, practical and non-invasive aid in the diagnosis of neuromuscular disorders in children, that is able to discriminate between children with and without a neuromuscular disorder and between neurogenic disorders and myopathies with high predictive values.
This item appears in the following Collection(s)
- Academic publications [205105]
- Electronic publications [103313]
- Faculty of Medical Sciences [81055]
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