[Bilateral lesions of the basal ganglia as a sign of chronic carbon monoxide intoxication]
until further notice
SourceNederlands Tijdschrift voor Geneeskunde, 151, 15, (2007), pp. 868-873
Article / Letter to editor
Display more detailsDisplay less details
Donders Centre for Cognitive Neuroimaging
Nederlands Tijdschrift voor Geneeskunde
SubjectDCN 2: Functional Neurogenomics; DCN 3: Neuroinformatics; NCEBP 10: Human Movement & Fatigue; UMCN 3.2: Cognitive neurosciences; NCEBP 10: Human Movement & Fatigue
A 40-year-old, previously healthy man presented with a subacute coordination disorder and intermittent paraesthesias of the right arm that had begun several months before and had disappeared spontaneously within a few weeks. Neurological examination showed a mildly flattened nasolabial fold on the right side and subtle hypertonia of the right arm. A CT-scan of the brain revealed calcifications in the left caudate nucleus and putamen. Cerebral MRI showed markedly enlarged Virchow-Robin spaces bilaterally in the basal ganglia and extensive periventricular white matter lesions. The differential diagnosis of these radiological findings included carbon monoxide intoxication. Ancillary investigations excluded other causes for the radiological abnormalities, and a defective gas stove that produced carbon monoxide was found in the patient's house. Although carbon monoxide poisoning is relatively rare in the Netherlands, it remains important to be alert to the possibility of such exposure. Radiological findings, notably bilateral lesions of the basal ganglia, may point in the direction of the proper diagnosis.
Upload full text
Use your RU credentials (u/z-number and password) tolog in with SURFconextto upload a file for processing by the repository team.