Fulltext:
52016.pdf
Embargo:
until further notice
Size:
124.9Kb
Format:
PDF
Description:
Publisher’s version
Publication year
2007Source
European Journal of Surgical Oncology, 33, 8, (2007), pp. 951-5ISSN
Publication type
Article / Letter to editor
Display more detailsDisplay less details
Organization
Health Evidence
Pathology
Former Organization
Epidemiology, Biostatistics & HTA
Journal title
European Journal of Surgical Oncology
Volume
vol. 33
Issue
iss. 8
Page start
p. 951
Page end
p. 5
Subject
CTR 3: Translational research; NCEBP 1: Molecular epidemiology; ONCOL 3: Translational research; UMCN 1.2: Molecular diagnosis, prognosis and monitoring; UMCN 1.5: Interventional oncology; UMCN 5.4: Renal disordersAbstract
AIM: To determine the incidence of EMPD and to describe its epidemiology, treatment, survival and the risk of developing other malignancies. METHOD: All cases of EMPD, diagnosed between 1989 and 2001, were selected from the Netherlands Cancer Registry. RESULTS: In total, 178 cases of invasive and 48 cases of in situ EMPD had been registered. The overall relative 5-year survival for invasive tumours was 72%. Most patients with invasive as well as in situ cancer underwent surgery. Other malignancies were found in 32% of patients with invasive EMPD and 35% of patients with in situ EMPD. Patients had an increased risk of developing a second primary cancer (standardized incidence ratio: 1.7; 95% confidence interval 1.2-2.4). The most frequent localizations of the other cancers were the colorectum, the prostate, the breast and the extragenital skin. CONCLUSIONS: For EMPD, which is a rare disease in the Netherlands, there are no clear diagnostic and treatment guidelines. The prognosis is fairly good. A thorough search for other tumours is recommended for these patients.
This item appears in the following Collection(s)
- Academic publications [238441]
- Electronic publications [122537]
- Faculty of Medical Sciences [90373]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.