Subject:
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EBP 1: Determinants in Health and Disease NCEBP 1: Molecular epidemiology NCMLS 3: Growth and differentiation NCMLS 6: Genetics and epigenetic pathways of disease ONCOL 1: Hereditary cancer and cancer-related syndromes ONCOL 3: Translational research ONCOL 5: Aetiology, screening and detection UMCN 1.2: Molecular diagnosis, prognosis and monitoring UMCN 1.5: Interventional oncology UMCN 5.1: Genetic defects of metabolism NCMLS 3: Growth and differentiation |
Organization:
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Clinical Chemistry Health Evidence Urology Pathology |
Former Organization:
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Epidemiology, Biostatistics & HTA Radboud University Nijmegen Medical Centre
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Journal title:
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British Journal of Cancer
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Abstract:
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We investigated whether smoking is associated with mutations in the Von Hippel-Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations.
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