Teaching molecular genetics: Chapter 1--Background principles and methods of molecular biology.
SourcePediatric Nephrology, 21, 2, (2006), pp. 169-76
Article / Letter to editor
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Paediatrics - OUD tm 2017
SubjectIGMD 5: Health aging / healthy living; IGMD 9: Renal disorder; NCMLS 5: Membrane transport and intracellular motility; UMCN 5.3: Cellular energy metabolism; UMCN 5.4: Renal disorders
In this first chapter of the series "Teaching molecular genetics," an introduction to molecular genetics is presented. We describe the structure of DNA and genes and explain in detail the central dogma of molecular biology, that is, the flow of genetic information from DNA via RNA to polypeptide (protein). In addition, several basic and frequently used general molecular tools, such as restriction enzymes, Southern blotting, DNA amplification and sequencing are discussed, in order to lay the foundations for the forthcoming chapters.
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