[Thalidomide for the treatment of recurrent gastrointestinal blood loss due to intestinal angiodysplasias]
until further notice
SourceNederlands Tijdschrift voor Geneeskunde, 150, 36, (2006), pp. 1994-7
Article / Letter to editor
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Nederlands Tijdschrift voor Geneeskunde
SubjectIGMD 2: Molecular gastro-enterology and hepatology; NCMLS 5: Membrane transport and intracellular motility; ONCOL 1: Hereditary cancer and cancer-related syndromes; ONCOL 5: Aetiology, screening and detection; UMCN 5.1: Genetic defects of metabolism
Two female patients, 86 and 80 years of age, had been treated with blood transfusions for several years and several months, respectively, due to iron-deficiency anaemia caused by gastrointestinal blood loss. Angiodysplasias were detected and subsequently coagulated in the course of repeated gastroscopies and colonoscopies. Due to the failure of this treatment, treatment with thalidomide was started. Thereafter, the gastrointestinal bleeding stopped and there was no longer any need for blood transfusions. Treatment with thalidomide seems an effective therapy for patients with frequently recurring gastrointestinal blood loss due to angiodysplasias who no longer tolerate conventional and invasive procedures due to their physical condition.
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