Subject:
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DCN 1: Perception and Action EBP 1: Determinants in Health and Disease UMCN 3.2: Cognitive neurosciences |
Organization:
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Donders Centre for Cognitive Neuroimaging |
Former Organization:
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F.C. Donders Centre for Cognitive Neuroimaging
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Journal title:
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International Journal of Neuroscience
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Abstract:
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The authors investigated the role of visuo-spatial attention in an antisaccade task using event-related potentials (ERPs) in schizophrenia patients compared to healthy controls. ERPs between 80-130 ms (P100) after stimulus onset showed differences between pro- and antisaccades only for controls and can be related to the suppression of irrelevant stimulus features. Between 150-180 ms (N100), a larger amplitude for anti-compared to prosaccades over centroparietal electrodes showed that processes of visuo-spatial attention seem to be engaged in performance of the antisaccade task. Left temporo-occipitally, this activity was only evident in schizophrenia patients, possibly reflecting additional neuronal recruitment in order to perform the antisaccade task successfully.
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