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Publication year
2005Source
British Journal of Surgery, 92, 11, (2005), pp. 1363-7ISSN
Publication type
Article / Letter to editor
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Organization
Surgery
Urology
Nuclear Medicine
Journal title
British Journal of Surgery
Volume
vol. 92
Issue
iss. 11
Page start
p. 1363
Page end
p. 7
Subject
N4i 1: Pathogenesis and modulation of inflammation; ONCOL 3: Translational research; ONCOL 5: Aetiology, screening and detection; UMCN 1.1: Functional ImagingAbstract
BACKGROUND: The aim of this prospective study was to evaluate the role of fluorodeoxyglucose positron emission tomography (FDG-PET) in the staging of high-risk women with primary or recurrent breast cancer. METHODS: FDG-PET was performed in 42 women with a primary breast cancer and unfavourable characteristics, or who had a suspected relapse. FDG-PET and conventional staging methods were compared. In case of abnormality on FDG-PET, confirmation was always attempted. RESULTS: Increased uptake was found in five of 17 women with a primary cancer. In the 25 women with a suspected relapse, FDG-PET showed increased uptake in 43 areas, 22 correctly confirming the area of suspected relapse and 21 indicating other sites of metastases. Compared with conventional imaging, FDG-PET revealed additional (confirmed) lesions in two women with primary cancers and three with relapse. Patient management was changed for five women. CONCLUSION: FDG-PET is a sensitive diagnostic method for the detection of distant metastatic disease. Its exact role in women with breast cancer remains to be defined.
This item appears in the following Collection(s)
- Academic publications [238441]
- Electronic publications [122523]
- Faculty of Medical Sciences [90373]
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