Independent prognostic effect of co-morbidity in lymphoma patients: results of the population-based Eindhoven Cancer Registry.
Publication year
2005Source
European Journal of Cancer, 41, 7, (2005), pp. 1051-7ISSN
Publication type
Article / Letter to editor

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Organization
Medical Oncology
Journal title
European Journal of Cancer
Volume
vol. 41
Issue
iss. 7
Page start
p. 1051
Page end
p. 7
Subject
UMCN 1.5: Interventional oncologyAbstract
The prevalence of co-morbidity among elderly lymphoma patients is associated with a decrease in the use of chemotherapy. This study assessed the independent prognostic effect of co-morbidity in 1551 unselected lymphoma patients, diagnosed between 1995 and 2001 in the area of the population-based Eindhoven Cancer Registry. The prevalence of serious co-morbidity was 58% for patients with Hodgkin's disease (HD) who were over 60 years of age and 66% for patients with non-Hodgkin's lymphoma (NHL) who were over 60 years of age. The administration of chemotherapy declined in the presence of co-morbidity for elderly patients with early-stage HD and elderly patients with aggressive NHL. Co-morbidity was associated with a 10-20% decline in 5-year survival. Whether less frequent application of chemotherapy in the presence of co-morbidity is justified as far as complications, prognosis and quality of life are concerned requires further investigation.
This item appears in the following Collection(s)
- Academic publications [227881]
- Faculty of Medical Sciences [86219]
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