Low salinity acclimation and thyroid hormone metabolizing enzymes in gilthead seabream (Sparus auratus)
SourceGeneral and Comparative Endocrinology, 152, 2, (2007), pp. 215-222
Article / Letter to editor
Display more detailsDisplay less details
Organismal Animal Physiology
General and Comparative Endocrinology
SubjectOrganismal Animal Physiology
We investigated the effect of acclimation to low salinity water of gilthead seabream (Sparus auratus), a euryhaline seawater teleost, on the activities of thyroid hormone-metabolizing enzymes in gills, kidney, and liver. Following acclimation to low salinity water, the plasma free thyroxine (T(4)) concentration increases 2.5-fold, and outer ring deiodination activities towards T(4), 3,5,3'-triiodothyronine (T(3)) and 3,3',5'-triiodothyronine (reverse T(3), rT(3)) in the gills are reduced by 20-32%. Conjugation (catalyzed by sulfotransferase and UDP-glucuronyltransferase) and deconjugation pathways (arylsulfatase, beta-glucuronidase) play a role in the biological activity of native and conjugated thyroid hormones. Branchial, renal, and hepatic activities of the enzymes involved in these metabolic pathways respond differentially to low salinity conditions. The results substantiate that thyroid hormones are involved in S. auratus osmoregulation, and that the gills are well equipped to play an important role in the modulation of plasma hormone titers.
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.