Improving quality control of whole slide images by explicit artifact augmentation
Publication year
2024Source
Scientific Reports, 14, 1, (2024), pp. 17847, article 17847ISSN
Publication type
Article / Letter to editor
Display more detailsDisplay less details
Organization
Pathology
Journal title
Scientific Reports
Volume
vol. 14
Issue
iss. 1
Page start
p. 17847
Subject
Pathology - Radboud University Medical CenterAbstract
The problem of artifacts in whole slide image acquisition, prevalent in both clinical workflows and research-oriented settings, necessitates human intervention and re-scanning. Overcoming this challenge requires developing quality control algorithms, that are hindered by the limited availability of relevant annotated data in histopathology. The manual annotation of ground-truth for artifact detection methods is expensive and time-consuming. This work addresses the issue by proposing a method dedicated to augmenting whole slide images with artifacts. The tool seamlessly generates and blends artifacts from an external library to a given histopathology dataset. The augmented datasets are then utilized to train artifact classification methods. The evaluation shows their usefulness in classification of the artifacts, where they show an improvement from 0.10 to 0.01 AUROC depending on the artifact type. The framework, model, weights, and ground-truth annotations are freely released to facilitate open science and reproducible research.
This item appears in the following Collection(s)
- Academic publications [243859]
- Electronic publications [130593]
- Faculty of Medical Sciences [92795]
- Open Access publications [104904]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.