Left and right ventricular strain-volume/area loops: a narrative review of current physiological understanding and potential clinical value.
Publication year
2024Source
Echo Research and Practice, 11, 1, (2024), pp. 12, article 12ISSN
Publication type
Article / Letter to editor
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Organization
Cardiology
Medical Biosciences
Journal title
Echo Research and Practice
Volume
vol. 11
Issue
iss. 1
Page start
p. 12
Subject
Cardiology - Radboud University Medical Center; Medical Biosciences - Radboud University Medical CenterAbstract
Traditionally, echocardiography is used for volumetric measurements to aid in assessment of cardiac function. Multiple echocardiographic-based assessment techniques have been developed, such as Doppler ultrasound and deformation imaging (e.g., peak global longitudinal strain (GLS)), which have shown to be clinically relevant. Volumetric changes across the cardiac cycle can be related to deformation, resulting in the Ventricular Strain-Volume/Area Loop. These Loops allow assessment of the dynamic relationship between longitudinal strain change and volumetric change across both systole and diastole. This integrated approach to both systolic and diastolic function assessment may offer additional information in conjunction with traditional, static, measures of cardiac function or structure. The aim of this review is to summarize our current understanding of the Ventricular Strain-Volume/Area Loop, describe how acute and chronic exposure to hemodynamic stimuli alter Loop characteristics, and, finally, to outline the potential clinical value of these Loops in patients with cardiovascular disease. In summary, several studies observed Loop changes in different hemodynamic loading conditions and various (patho)physiological conditions. The diagnostic and prognostic value, and physiological interpretation remain largely unclear and have been addressed only to a limited extent.
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- Academic publications [244262]
- Electronic publications [131202]
- Faculty of Medical Sciences [92892]
- Open Access publications [105228]
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