TY  - JOUR
AU  - Roerink, M.E.
AU  - Schaaf, M.E. van der
AU  - Hawinkels, L.J.A.C.
AU  - Raijmakers, R.P.H.
AU  - Knoop, H.
AU  - Joosten, L.A.B.
AU  - Meer, J.W.M. van der
PY  - 2018
UR  - http://hdl.handle.net/2066/195865
TI  - Pitfalls in cytokine measurements - Plasma TGF-beta 1 in chronic fatigue syndrome
EP  - 313
SN  - 0300-2977
IS  - iss. 7
SP  - 310
JF  - Netherlands Journal of Medicine
VL  - vol. 76
PS  - 4 p.
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/195865/195865.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Spierings, E.J.W.
AU  - Meer, J.W.M. van der
AU  - Simon, A.
PY  - 2017
UR  - http://hdl.handle.net/2066/177416
AB  - A patient presented with recurrent episodes of fever and skin rash for eight years. DNA analysis of the NLRP3 gene revealed a mutation associated with autoinflammatory disease. After an initial positive response to the biological anakinra, the patient deteriorated. Reassessment revealed recurrent erysipelas. In conclusion, sometimes erysipelas-like skin rash is real erysipelas, and DNA results are not always the final answer.
TI  - Pitfall of modern genetics: recurrent erysipelas masquerading as autoinflammatory disease
EP  - 249
SN  - 0300-2977
IS  - iss. 6
SP  - 247
JF  - Netherlands Journal of Medicine
VL  - vol. 75
ER  - 
TY  - JOUR
AU  - Keijmel, S.P.
AU  - Kasteren, M.E.E. van
AU  - Blokx, W.A.M.
AU  - Meer, J.W.M. van der
AU  - Rossum, M.M. van
AU  - Bleeker-Rovers, C.P.
PY  - 2015
UR  - http://hdl.handle.net/2066/154914
AB  - Cutaneous hyperpigmentation is a well-known side effect of tetracyclines, but doxycycline-induced cutaneous hyperpigmentation has only been described in one patient with a therapeutic dosage of doxycycline, and in one patient using suprapharmacological doses. We describe four patients with cutaneous hyperpigmentation in previously unaffected skin, and speculate that this was due to treatment with doxycycline in therapeutic doses. After cessation of therapy, the hyperpigmentation diminished in all four patients, illustrating the need for recognition and timely cessation of therapy.
TI  - Cutaneous hyperpigmentation induced by doxycycline: a case series
EP  - 40
SN  - 0300-2977
IS  - iss. 1
SP  - 37
JF  - Netherlands Journal of Medicine
VL  - vol. 73
ER  - 
TY  - JOUR
AU  - Veerdonk, F.L. van de
AU  - Netea, M.G.
AU  - Dinarello, C.A.
AU  - Meer, J.W.M. van der
PY  - 2011
UR  - http://hdl.handle.net/2066/96628
TI  - Anakinra for the inflammatory complications of chronic granulomatous disease
EP  - 95
SN  - 0300-2977
IS  - iss. 2
SP  - 95
JF  - Netherlands Journal of Medicine
VL  - vol. 69
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/96628/96628.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Kullberg, B.J.
AU  - Berende, A.
AU  - Meer, J.W.M. van der
PY  - 2011
UR  - http://hdl.handle.net/2066/97419
TI  - The challenge of Lyme disease: tired of the Lyme wars
EP  - 100
SN  - 0300-2977
IS  - iss. 3
SP  - 98
JF  - Netherlands Journal of Medicine
VL  - vol. 69
ER  - 
TY  - JOUR
AU  - Vriens, D.
AU  - Geus-Oei, L.F. de
AU  - Flucke, U.E.
AU  - Kogel, A.J. van der
AU  - Oyen, W.J.G.
AU  - Vierhout, M.E.
AU  - Meer, J.W.M. van der
PY  - 2010
UR  - http://hdl.handle.net/2066/88574
TI  - Benign uterine uptake of FDG: a case report and review of literature.
EP  - 380
SN  - 0300-2977
IS  - iss. 9
SP  - 379
JF  - Netherlands Journal of Medicine
VL  - vol. 68
N1  - 1 september 2010
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/88574/88574_pub.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Leij, F. van der
AU  - Drenth, J.P.H.
AU  - Joosten, L.A.B.
AU  - Morsche, R.H.M. te
AU  - Verweij, P.E.
AU  - Jong, D. de
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
PY  - 2010
UR  - http://hdl.handle.net/2066/87277
AB  - Infection with Yersinia enterocolitica leads to a self-limiting disease, but in a small number of cases a protracted course can develop. The host genetic factors contributing to the advancement of the disease to the chronic phase are not known. We describe a patient suffering from an abdominal inflammatory mass due to chronic yersiniosis. Functional assays revealed defects in the recognition of flagellin by Toll-like receptor 5 (TLR5) and of muramyl dipeptide by NOD2, leading to a defective inflammatory response to Yersinia enterocolitica. Genetic sequencing showed that the patient was compound heterozygous for five different mutations in TLR5, while being homozygous for the 3020insC NOD2 mutation. In conclusion, we describe a patient in whom specific defects in the TLR5 and NOD2 recognition pathways led to chronic yersiniosis.
TI  - Chronic yersiniosis due to defects in the TLR5 and NOD2 recognition pathways.
EP  - 315
SN  - 0300-2977
IS  - iss. 10
SP  - 310
JF  - Netherlands Journal of Medicine
VL  - vol. 68
N1  - 1 oktober 2010
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/87277/87277.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Bodar, E.J.
AU  - Simon, A.
AU  - Visser, M. de
AU  - Meer, J.W.M. van der
PY  - 2009
UR  - http://hdl.handle.net/2066/81758
AB  - A 62-year-old patient had suffered from severe cold intolerance with an urticarial rash and oropharyngeal angio-oedema upon cold exposure since early childhood. This could be provoked by the ice cube test and by exposure in a cold room. Her family history was negative, and she did not carry any mutations in the NRLP3 gene. Treatment with IL-1 receptor antagonist anakinra resulted in complete resolution of these symptoms, with a radical beneficial change in her quality of life. In recent years this patient had developed progressive neurological symptoms leading to a diagnosis of amyotrophic lateral sclerosis (ALS), which seems unrelated to the idiopathic cold urticaria. The neurological symptoms did not respond to anakinra treatment and were eventually fatal. Conclusion: We describe the first case of IL-1RA treatment in idiopathic cold urticaria with good response. Anakinra had no effect on the progression of her symptoms of ALS.
TI  - Complete remission of severe idiopathic cold urticaria on interleukin-1 receptor antagonist (anakinra).
EP  - 305
SN  - 0300-2977
IS  - iss. 9
SP  - 302
JF  - Netherlands Journal of Medicine
VL  - vol. 67
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Hoitink, O.
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
AU  - Raymakers, R.A.P.
PY  - 2008
UR  - http://hdl.handle.net/2066/69628
AB  - BACKGROUND: Patients with hairy cell leukaemia (HCL) have an increased susceptibility to intracellular pathogens, such as mycobacteria and Listeria. Although several abnormalities of T-cell populations have been described in HCL, the effector mechanism responsible for the increased susceptibility to infections is not known. METHODS: Blood was collected from 11 patients with HCL and 22 age- and gender-matched volunteers. Proinflammatory cytokine production by freshly isolated mononuclear cells was stimulated with either lipopolysaccharide or various heat-killed microorganisms. Cytokine concentrations were assessed by specific ELISAs. RESULTS: We demonstrate that mononuclear cells harvested from HCL patients have a specific defect of IFNgamma production when stimulated with a broad panel of bacterial stimuli. In contrast, the production of other proinflammatory cytokines, such as TNF, IL-1beta and IL-6, did not differ between HCL patients and controls. CONCLUSION: The specific defect in IFNgamma production may play a role in the susceptibility of patients with hairy cell leukaemia towards intracellular pathogens.
TI  - Defective interferon-gamma production in patients with hairy cell leukaemia.
EP  - 334
SN  - 0300-2977
IS  - iss. 8
SP  - 340
JF  - Netherlands Journal of Medicine
VL  - vol. 66
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/69628/69628.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
PY  - 2008
UR  - http://hdl.handle.net/2066/70721
TI  - 50 years Netherlands Journal of Medicine - 2002, reshaping the journal.
EP  - 399
SN  - 0300-2977
IS  - iss. 9
SP  - 398
JF  - Netherlands Journal of Medicine
VL  - vol. 66
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/70721/70721.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Koster, J.B.
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
PY  - 2007
UR  - http://hdl.handle.net/2066/53478
TI  - Recurrent erysipelas despite antibiotic prophylaxis: an analysis from case studies.
EP  - 94
SN  - 0300-2977
IS  - iss. 3
SP  - 89
JF  - Netherlands Journal of Medicine
VL  - vol. 65
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/53478/53478.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
AU  - Gier, A.M. de
AU  - Swaaij, W.P.
AU  - Katan, M.B.
PY  - 2007
UR  - http://hdl.handle.net/2066/53147
TI  - Independent medical research.
EP  - 126
SN  - 0300-2977
IS  - iss. 4
SP  - 124
JF  - Netherlands Journal of Medicine
VL  - vol. 65
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/53147/53147.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Desar, I.M.E.
AU  - Weemaes, C.M.R.
AU  - Deuren, M. van
AU  - Meer, J.W.M. van der
PY  - 2007
UR  - http://hdl.handle.net/2066/51746
AB  - In this report we present four patients with reversible hypogammaglobulinaemia who required immunoglobulin substitution for several years. One patient had documented systemic lupus erythematosus (SLE), the other three patients had primary hypogammaglobulinaemia without known cause. Whereas the cessation of azathioprine therapy may have contributed to the recovery in the patient with SLE, the restoration of the immunoglobulin production in the other three patients occurred spontaneously. All four patients were IgA deficient when the hypogammaglobulinaemia was first detected and remained so after IgM and IgG production had recovered. Two of the three patients who also had anti-IgA antibodies started to produce anti-IgA again after stopping the immunoglobulin substitution. We conclude that recovery of hypogammaglobulinaemia is possible but rare. When recovery is suspected, we recommend that immunoglobulin substitution is stopped and the antibody response to vaccination is tested.
TI  - Reversible hypogammaglobulinaemia.
EP  - 385
SN  - 0300-2977
IS  - iss. 10
SP  - 381
JF  - Netherlands Journal of Medicine
VL  - vol. 65
ER  - 
TY  - JOUR
AU  - Desar, I.M.E.
AU  - Keuter, M.
AU  - Raemaekers, J.M.M.
AU  - Jansen, J.B.M.J.
AU  - Krieken, J.H.J.M. van
AU  - Meer, J.W.M. van der
PY  - 2006
UR  - http://hdl.handle.net/2066/49902
AB  - We describe two patients with common variable immunodeficiency (CVID) who developed extranodal marginal zone lymphoma (formerly described as mucosa-associated lymphoid tissue lymphoma or MALT lymphoma). One patient, with documented pernicious anaemia and chronic atrophic gastritis with metaplasia, developed a Helicobacter pylori-positive extranodal marginal zone lymphoma in the stomach. Three triple regimens of antibiotics were necessary to eliminate the H. pylori, after which the lymphoma completely regressed. Patient B had an H. pylori-negative extranodal marginal zone lymphoma of the parotid gland, which remarkably regressed after treatment with clarithromycin. Reviewing the literature, we found eight cases of extranodal marginal zone lymphoma complicating CVID, but probably many more cases labelled as non-Hodgkin's lymphoma are hidden in the literature. Until more data are available on the predictive value of noninvasive screening for pathology of the stomach, we recommend endoscopy to assess the gastric status in CVID patients in order to detect these malignancies at an early stage. Elimination of H. pylori infection is the treatment of choice in Helicobacter-positive extranodal marginal zone lymphoma. The possibility of elimination failure, most probably due to frequent and prolonged exposure to antibiotics in this patient group, should be taken into account. Treatment with antibiotics in Helicobacter-negative extranodal marginal zone lymphoma must be considered.
TI  - Extranodal marginal zone (MALT) lymphoma in common variable immunodeficiency.
EP  - 140
SN  - 0300-2977
IS  - iss. 5
SP  - 136
JF  - Netherlands Journal of Medicine
VL  - vol. 64
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Ferwerda, G.
AU  - Jong, D.J. de
AU  - Girardin, S.E.
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
PY  - 2005
UR  - http://hdl.handle.net/2066/48909
AB  - BACKGROUND: Mutations of the NOD2 gene increase the susceptibility of humans to Crohn's disease. NOD2 is a cytoplasmic receptor for the bacterial product peptidoglycan. There is considerable controversy in the literature whether the most common mutation in Crohn's disease, the 3020insC NOD2, leads to a loss of function, i.e. decreased cytokine production, or to the reverse, i.e. a gain of function. In previous papers we proposed the former, since we could show decreased cytokine production with a net proinflammatory status after exposure to muramyl dipeptide (MDP). METHODS: Because of recent data in the literature showing increased interleukin-beta (IL-1beta) production in mice with the corresponding NOD2 mutation, we investigated the production of this cytokine by cells of patients with Crohn's disease, either homozygous or heterozygous for the 3020insC mutation, and compared it with that of patients with Crohn's disease bearing the wild-type allele. RESULTS: A strongly decreased production of IL-1beta by peripheral mononuclear cells was found upon exposure to either peptidoglycan or peptidoglycan-derived MDP in homozygous patients bearing the 3020insC NOD2mutation. CONCLUSION: This sustains the hypothesis that the 3020insC mutation in the human NOD2 gene leads to a loss-of-function phenotype.
TI  - NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype.
EP  - 308
SN  - 0300-2977
IS  - iss. 8
SP  - 305
JF  - Netherlands Journal of Medicine
VL  - vol. 63
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/48909/48909.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
AU  - Popa, C.
AU  - Netea, M.G.
PY  - 2005
UR  - http://hdl.handle.net/2066/48130
AB  - Anticytokine strategies probably represent the most important breakthrough in the treatment of inflammatory diseases in the last decade. However, blocking the bioactivity of proinflammatory cytokines, crucial activators of host defence, has proved to be accompanied by an increased susceptibility to infections, especially with Mycobacteria, Salmonellae and fungal pathogens. Multiple mechanisms for these side effects have been proposed, such as inhibition of gamma-interferon production, decreased expression of pattern-recognition receptors, and leucocyte apoptosis. Caution is therefore warranted when these treatments are given to patients with an increased risk for infections. A range of side effects other than infection have been reported.
TI  - Side effects of anticytokine strategies.
EP  - 80
SN  - 0300-2977
IS  - iss. 3
SP  - 78
JF  - Netherlands Journal of Medicine
VL  - vol. 63
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/48130/48130.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Schouten, J.A.
AU  - Hulscher, M.E.J.L.
AU  - Natsch, S.S.
AU  - Grol, R.P.T.M.
AU  - Meer, J.W.M. van der
PY  - 2005
UR  - http://hdl.handle.net/2066/47995
AB  - Control measures for the use of antibiotics are essential because of the potential harmful consequences of side effects. Various methods have been developed to help curb undesirable antibiotic prescription. We performed a survey in Dutch secondary care hospitals (response rate 73%) to make an inventory of these measures and elucidate possible shortcomings. Almost every hospital was using an antibiotic formulary (97%), sometimes supported by extra restrictions in antibiotic choice (55%). Local practice guidelines (95%) were commonly present, but effective implementation, for example using intranet applications, could be improved (21%). National guidelines had received little attention in the composition process of local guidelines (19%). Other measures such as educational programmes for specialists (11%) and feedback on antibiotic prescription (52%) remained largely underused, although their effective implementation may optimise antibiotic prescription in hospitals.
TI  - Antibiotic control measures in Dutch secondary care hospitals.
EP  - 30
SN  - 0300-2977
IS  - iss. 1
SP  - 24
JF  - Netherlands Journal of Medicine
VL  - vol. 63
ER  - 
TY  - JOUR
AU  - Bodar, E.J.
AU  - Hilst, J.C.H. van der
AU  - Drenth, J.P.H.
AU  - Meer, J.W.M. van der
AU  - Simon, A.
PY  - 2005
UR  - http://hdl.handle.net/2066/48588
AB  - BACKGROUND: Hyper-IgD and periodic fever syndrome (HIDS) is an hereditary autoinflammatory syndrome, characterised by recurrent inflammatory attacks. Treatment of HIDS is difficult, although simvastatin is beneficial and etanercept might be effective. Studying the treatment of a rare periodic syndrome is complicated by the varying frequency and severity of symptoms and low prevalence. Our aim was to develop a system of clinical observations to evaluate effectiveness of treatment-on-demand. METHODS: Seven fever episodes in three HIDS patients were monitored, with and without administration of etanercept or anakinra. We developed a clinical score, which includes 12 symptoms. In one patient, inflammatory attacks were provoked by vaccination. RESULTS AND CONCLUSIONS: At the onset of an attack, all patients reported a clinical score between 20 and 25. The score was used to quantify severity and define the end of an attack. Reproducible monitoring of inflammatory episodes was difficult, even in this pilot study. The effect of early administration of etanercept was variable. In one patient, a fever episode could be readily provoked within 12 to 24 hours by vaccination. In this patient, the IL-1ra analogue anakinra was more successful in aborting the inflammatory attack than etanercept. We propose that this vaccination model will allow evaluation of treatment-on-demand in a controlled setting.
TI  - Effect of etanercept and anakinra on inflammatory attacks in the hyper-IgD syndrome: introducing a vaccination provocation model.
EP  - 264
SN  - 0300-2977
IS  - iss. 7
SP  - 260
JF  - Netherlands Journal of Medicine
VL  - vol. 63
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/48588/48588.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Verhage, D.F.
AU  - Telgt, D.S.C.
AU  - Bousema, T.
AU  - Hermsen, C.C.
AU  - Gemert, G.J.A. van
AU  - Meer, J.W.M. van der
AU  - Sauerwein, R.W.
PY  - 2005
UR  - http://hdl.handle.net/2066/47503
AB  - BACKGROUND: Human experimental malaria infections have been safely carried out previously. The objective of this study was to evaluate infection rates and clinical safety of different protocols for human experimental malaria induced by Plasmodium falciparum-infected mosquitoes. METHODS: Thirty nonimmune volunteers were infected by bites of 1-2 or 4-7 Anopheles stephensi mosquitoes infected with the NF54 strain of P. falciparum. RESULTS: A 100 or 50% infection rate was obtained after bites of 4-7 and 1-2 infected mosquitoes, respectively. Median prepatent period was 8.8 days. The most common symptoms after a median incubation time of eight days were headache, malaise/fatigue and fever. There was no significant difference in clinical and parasitological presentation between groups infected by 4-7 or 1-2 mosquitoes. Delay of treatment by maximally 48 hours after the first positive thick smear was generally well tolerated but fever was higher and more frequently observed. The most prominent laboratory abnormality was uncomplicated thrombocytopenia. Two volunteers with parasitaemia developed psychiatric side effects after chloroquine treatment. CONCLUSION: With stringent inclusion criteria, close monitoring and immediate administration of treatment upon detection of parasitaemia, experimental human malaria challenges can be considered safe and generally well tolerated.
TI  - Clinical outcome of experimental human malaria induced by Plasmodium falciparum-infected mosquitoes.
EP  - 58
SN  - 0300-2977
IS  - iss. 2
SP  - 52
JF  - Netherlands Journal of Medicine
VL  - vol. 63
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/47503/47503.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
AU  - Ottenhoff, T.H.M.
AU  - Netea, M.G.
AU  - Furth, R. van
AU  - Jungh, B.M. de
AU  - Kuijpers, T.W.
AU  - McAdam, K.P.W.J.
PY  - 2004
UR  - http://hdl.handle.net/2066/13847
PB  - Van zuiden communications
TI  - Discussion following lecture by T.H.M. Ottenhoff
EP  - 41
SN  - 0300-2977
IS  - iss. 3
SP  - 40
JF  - Netherlands Journal of Medicine
VL  - vol. 62
ER  - 
TY  - JOUR
AU  - Stuyt, P.M.J.
AU  - Graaf, J. de
AU  - Meer, J.W.M. van der
PY  - 2004
UR  - http://hdl.handle.net/2066/13816
PB  - Van zuiden communications
TI  - Who does become an internist?
EP  - 101
SN  - 0300-2977
IS  - iss. 3
SP  - 98
JF  - Netherlands Journal of Medicine
VL  - vol. 62
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/13816/13816.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Stuyt, P.M.J.
AU  - Graaf, J. de
AU  - Meer, J.W.M. van der
PY  - 2004
UR  - http://hdl.handle.net/2066/59054
AB  - Internal medicine is a broad medical speciality and choosing the residency programme opens up a variety of career tracks. Despite this broad choice of subspecialities, we found that within our residency programme for internal medicine in the Nijmegen region between 1981 and 2000, 29% of the residents did not become internists but switched to other medical specialities. To further complicate the efficiency of the residency programme, about 20% of the residents who became internists did not finish within six years, but had a delay of two years due to combined internal medicine/PhD tracks (the training for internist/clinical investigator). In another 20% there is a delay of six to 12 months due to part-time training tracks as well as to (multiple) pregnancies of female residents and parental leave of both sexes. Our data imply that nationwide data are urgently needed to re-evaluate the manpower planning for internal medicine by taking into consideration not only the number of residents starting in the residency programme but also to include the number of residents who actually do become internists.
TI  - Who does become an internist?
EP  - 101
SN  - 0300-2977
IS  - iss. 3
SP  - 98
JF  - Netherlands Journal of Medicine
VL  - vol. 62
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/59054/59054.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19729
PB  - Van zuiden communications
TI  - Immunomodulation by antimicrobial drugs
EP  - 234
SN  - 0300-2977
IS  - iss. 7
SP  - 233
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Aken, J. van
AU  - Mulder, A.H.
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19737
PB  - Van zuiden communications
TI  - Skin lesions on the foot
EP  - 257
SN  - 0300-2977
IS  - iss. 8
SP  - 257
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Bleeker-Rovers, C.P.
AU  - Bredie, S.J.H.
AU  - Meer, J.W.M. van der
AU  - Corstens, F.H.M.
AU  - Oyen, W.J.G.
PY  - 2003
UR  - http://hdl.handle.net/2066/19718
PB  - Van zuiden communications
TI  - F-18-fluorodeoxyglucose positron emission tomography in diagnosis and follow-up of patients with different types of vasculitis
EP  - 329
SN  - 0300-2977
IS  - iss. 10
SP  - 323
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Eijkhout, H.W.
AU  - Broek, P.J. van den
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19721
PB  - Van zuiden communications
TI  - Substitution therapy in immunodeficient patients with anti-IgA antibodies or severe adverse reactions to previous immunoglobulin therapy
EP  - 217
SN  - 0300-2977
IS  - iss. 6
SP  - 213
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - The, G.K.H.
AU  - Prins, J.
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19747
PB  - Van zuiden communications
TI  - The effect of granisetron, a 5-HT3 receptor antagonist, in the treatment of chronic fatigue syndrome patients - a pilot study
EP  - 289
SN  - 0300-2977
IS  - iss. 9
SP  - 285
JF  - Netherlands Journal of Medicine
VL  - vol. 61
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/19747/19747the.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Stuyt, P.M.J.
AU  - Vries Robbe, P.F. de
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19743
PB  - Van zuiden communications
TI  - Why don't medical textbooks teach? The lack of logic in the differential diagnosis
EP  - 387
SN  - 0300-2977
IS  - iss. 11
SP  - 383
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Graaf, C.A.A. van der
AU  - Netea, M.G.
AU  - Drenth, J.P.H.
AU  - Morsche, R.H.T.
AU  - Meer, J.W.M. van der
AU  - Kullberg, B.J.
PY  - 2003
UR  - http://hdl.handle.net/2066/19725
PB  - Van zuiden communications
TI  - Candida-specific interferon-gamma deficiency and Toll-like receptor polymorphisms in patients with chronic mucocutaneous candidiasis
EP  - 369
SN  - 0300-2977
IS  - iss. 11
SP  - 365
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Prins, J.B.
AU  - Elving, L.D.
AU  - Koning, H.
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/19738
PB  - Van zuiden communications
TI  - Diagnosing chronic fatigue syndrome: comparison of a protocol and computerised questionnaires
EP  - 126
SN  - 0300-2977
IS  - iss. 4
SP  - 120
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Stuyt, P.M.J.
AU  - Vries Robbé, P.F. de
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/144404
AB  - Medical textbooks are an important aid in the process of diagnosing and treating patients. Medical students use these books to acquire the skills necessary for this process, while medical teachers and experienced doctors use them for teaching these competences. We posed the question whether medical textbooks are structured in such a way that medical students are taught to structure knowledge and to make a differential diagnosis in a logical way. Five major textbooks were compared with regard to four clinical problems (gastrointestinal bleeding, anaemia, oedema and heart failure). The presentation appeared to be very variable in respect of logic and systematic arrangement. In fact, it was disappointing that even in well-reputed textbooks, a systematic approach is lacking. We feel there is a need for improvement, in order to facilitate the learning of medical students and to enhance their abilities in clinical problem solving.
TI  - Why don't medical textbooks teach? The lack of logic in the differential diagnosis.
EP  - 387
SN  - 0300-2977
IS  - iss. 11
SP  - 383
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Prins, J.B.
AU  - Elving, L.D.
AU  - Koning, H.
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/185008
AB  - BACKGROUND: In the context of outpatient care and within the framework of scientific research, guidelines and measuring instruments have been developed to help improve CFS diagnostics. The purpose of this study was to measure the agreement between the evaluations of chronically fatigued patients by physicians using a CFS protocol and by researchers using computerised questionnaires. METHODS: The sample consisted of 516 patients referred to an internal medicine outpatient clinic with complaints of chronic fatigue. Retrospectively the medical records and the computerised questionnaires were checked separately and compared to see whether the criteria for diagnosis of CFS had been met. In addition, the reasons for not diagnosing CFS were evaluated. RESULTS: Agreement between the physicians' and the researchers' evaluations was 84%. Disagreement mostly concerned severity of fatigue and functional impairment, or premorbid exclusion criteria. A physical cause for the chronic fatigue was only found in 3% of the cases. CONCLUSIONS: For physicians, questionnaire assessment may be complementary to the CFS protocol in optimising the process of diagnosing CFS.
TI  - Diagnosing chronic fatigue syndrome: comparison of a protocol and computerised questionnaires.
EP  - 126
SN  - 0300-2977
IS  - iss. 4
SP  - 120
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Eijkhout, H.
AU  - Broek, P.J.J.A. van den
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/186418
AB  - BACKGROUND: Patients with common variable immunodeficiency often suffer from recurrent bacterial infections. Administration of immunoglobulins is a well-established treatment to reduce the frequency and severity of these infections. However, in patients with anti-IgA antibodies or side effects to previous immunoglobulin substitution therapy, administration of immunoglobulins may lead to anaphylactoid reactions. OBJECTIVE: To describe the feasibility of immunoglobulin substitution therapy in patients with anti-IgA antibodies or side effects to previous immunoglobulins. METHODS: A retrospective study was conducted in two university hospital outpatient clinics. Fourteen patients with common variable immunodeficiency were found to have circulating anti-IgA antibodies or have experienced severe reactions to previously administered blood products. RESULTS: In eight out of 15 patients side effects to immunoglobulins and/or blood transfusions had occurred previously. In four patients these reactions were due to anti-IgA antibodies. No side effects were observed when human immunoglobulin 16% was given by subcutaneous infusion. In all patients with anti-IgA antibodies, as well as in those without, subcutaneous immunoglobulins were well tolerated. In some patients antibodies disappeared and therapy could be changed into intravenous immunoglobulin administration. CONCLUSIONS: Patients with serious side effects to previous immunoglobulin therapy and/or blood transfusions can be safely treated with subcutaneous immunoglobulins and, if necessary, with intravenous immunoglobulins at a later point in time.
TI  - Substitution therapy in immunodeficient patients with anti-IgA antibodies or severe adverse reactions to previous immunoglobulin therapy.
EP  - 217
SN  - 0300-2977
IS  - iss. 6
SP  - 213
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - The, G.K.H.
AU  - Prins, J.B.
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2003
UR  - http://hdl.handle.net/2066/199417
AB  - OBJECTIVE: To explore the effect of granisetron, a 5-HT3 antagonist, on fatigue and functional impairment in patients with chronic fatigue syndrome (CFS). METHODS: Five female patients were eligible to receive oral granisetron for one month (1 mg a day for the first two weeks and 2 mg a day for the second two weeks). The patients had to be between 18 and 65 years of age and suffering from CFS according to the CDC criteria. The effect was assessed by pre- and post-testing, using validated instruments designed to assess the different dimensions of CFS. Treatment response was also evaluated by visual analogue scales (VAS) for fatigue. Analysis was based on intention to treat. RESULTS: Treatment with granisetron resulted in significant improvement in fatigue severity and functional impairment. Activity level showed no significant increase. CONCLUSION: The promising results of this study have encouraged us to perform a placebo-controlled, double-blind study to evaluate the efficacy of 5-HT3 receptor antagonists in the treatment of CFS.
TI  - The effect of granisetron, a 5-HT3 receptor antagonist, in the treatment of chronic fatigue syndrome patients--a pilot study.
EP  - 289
SN  - 0300-2977
IS  - iss. 9
SP  - 285
JF  - Netherlands Journal of Medicine
VL  - vol. 61
ER  - 
TY  - JOUR
AU  - Swinkels, D.W.
AU  - Aalbers, N.
AU  - Elving, L.D.
AU  - Bleijenberg, G.
AU  - Swanink, C.M.A.
AU  - Meer, J.W.M. van der
PY  - 2002
UR  - http://hdl.handle.net/2066/19707
PB  - Van zuiden communications
TI  - Primary haemochromatosis: a missed cause of chronic fatigue syndrome?
EP  - 433
SN  - 0300-2977
IS  - iss. 11
SP  - 429
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Hilst, J.C.H. van der
AU  - Smits, B.W.
AU  - Meer, J.W.M. van der
PY  - 2002
UR  - http://hdl.handle.net/2066/19690
PB  - Van zuiden communications
TI  - Hypogammaglobulinaemia: cumulative experience in 49 patients in a tertiary care institution
EP  - 147
SN  - 0300-2977
IS  - iss. 3
SP  - 140
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Schneeberger, P.M.
AU  - Vries, E. de
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
AU  - Koolen, M.I.
PY  - 2002
UR  - http://hdl.handle.net/2066/19694
PB  - Van zuiden communications
TI  - Th1/Th2 cytokine imbalance in a family with hyper-IgE syndrome
EP  - 353
SN  - 0300-2977
IS  - iss. 9
SP  - 349
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
PY  - 2002
UR  - http://hdl.handle.net/2066/19692
PB  - Van zuiden communications
TI  - The truth in reviews
EP  - 191
SN  - 0300-2977
IS  - iss. 5
SP  - 191
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Swinkels, D.W.
AU  - Aalbers, N.
AU  - Elving, L.D.
AU  - Bleijenberg, G.
AU  - Swanink, C.M.A.
AU  - Meer, J.W.M. van der
PY  - 2002
UR  - http://hdl.handle.net/2066/186661
TI  - Primary haemochromatosis: a missed cause of chronic fatigue syndrome?
EP  - 433
SN  - 0300-2977
IS  - iss. 11
SP  - 429
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Netea, M.G.
AU  - Schneeberger, P.M.
AU  - Vries, E. de
AU  - Kullberg, B.J.
AU  - Meer, J.W.M. van der
AU  - Koolen, M.
PY  - 2002
UR  - http://hdl.handle.net/2066/185494
AB  - BACKGROUND: Hyperimmunoglobulin E (hyper-IgE) syndrome is a rare immunodeficiency characterised by recurrent skin and respiratory tract infections, skeletal and dental abnormalities, chronic eczema, and elevated serum IgE. We describe a family with four hyper-IgE syndrome patients (38, 37, 30 and 7 years old), in which we investigated the cytokine response to both specific and non-specific stimulation. METHODS: Whole blood from patients and volunteers was stimulated for either 24 or 48h at 37 degrees C with heat-killed Staphylococcus, C. albicans or a combination of IL-12 and IL-18. Cytokine concentrations in the plasma were measured by specific radioimmuno-assays or ELISA. RESULTS: Serum IgE ranged from 5,000 to 16,670 IU/ml, and neutrophil chemotaxis was normal in all four patients. Tumour necrosis factor, interleukin (IL)-1beta, IL-6 and IL-8 production after stimulation of whole-blood cultures with lipopolysaccharide or heat-killed S. aureus did not differ between the adult patients and four healthy controls. In contrast, when blood from patients and controls was stimulated with heat-killed S. aureus or C. albicans, a severe imbalance towards a Th2 phenotype was found, with 10- to 30-fold reduction in the IFNgamma/IL-10 ratios in the hyper-IgE syndrome patients. The IFNgamma production in the patients was less severely impaired when blood was non-specifically stimulated with a combination of IL-18 and IL-12. CONCLUSION: In this family with hyper-IgE syndrome, the imbalance in the Th1/Th2 cytokine production may have been involved in the pathogenesis of the recurrent infections and/or chronic eczema characteristic of this disease.
TI  - Th1/Th2 cytokine imbalance in a family with hyper-IgE syndrome.
EP  - 353
SN  - 0300-2977
IS  - iss. 9
SP  - 349
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Hilst, J.C.H. van der
AU  - Smits, B.W.
AU  - Meer, J.W.M. van der
PY  - 2002
UR  - http://hdl.handle.net/2066/147364
AB  - In this paper, clinical data of 49 adult patients with agammaglobulinaemia (syn. hypogammaglobulinaemia), 15 cases of X-linked agammaglobulinaemia (XLA) and 34 of common variable immunodeficiency (CVID) are reviewed. Although immunoglobulin substitution largely abolished life-threatening respiratory tract infections, considerable infectious and non-infectious morbidity was still encountered in these patients. Almost all patients suffered from chronic or recurrent upper and lower airway infections, mainly caused by Haemophilus influenzae and pneumococci. The lower respiratory tract infections led to cumulative damage to the respiratory tract, especially in XLA patients. Also the incidence of infections outside the respiratory tract (giardiasis, Campylobacter jejuni infections) was more common in XLA patients than in CVID patients. Nodular lymphoid hyperplasia was only found in CVID. A variety of other non-infectious complications were seen especially in CVID. Neoplastic complications occurred in nine patients (two cases of thymoma, two colorectal cancer, one gastric carcinoma, two haematological malignancies, two cases of skin cancer). Six patients died (five XLA patients and one CVID patient, from infectious and non-infectious causes).
TI  - Hypogammaglobulinaemia: cumulative experience in 49 patients in a tertiary care institution.
EP  - 147
SN  - 0300-2977
IS  - iss. 3
SP  - 140
JF  - Netherlands Journal of Medicine
VL  - vol. 60
ER  - 
TY  - JOUR
AU  - Nijenhuis, T.
AU  - Klasen, I.
AU  - Weemaes, C.M.R.
AU  - Preijers, F.
AU  - Vries, E. de
AU  - Meer, J.W.M. van der
PY  - 2001
UR  - http://hdl.handle.net/2066/19665
PB  - Elsevier science bv
TI  - Common variable immunodeficiency (CVID) in a family: an autosomal dominant mode of inheritance
EP  - 139
SN  - 0300-2977
IS  - iss. 3
SP  - 134
JF  - Netherlands Journal of Medicine
VL  - vol. 59
ER  - 
TY  - JOUR
AU  - Soetekouw, P.M.M.B.
AU  - Wevers, R.A.
AU  - Vreken, P.
AU  - Elving, L.D.
AU  - Janssen, A.J.M.
AU  - Veen, Y. van der
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2000
UR  - http://hdl.handle.net/2066/19644
PB  - Elsevier science bv
TI  - Normal carnitine levels in patients with chronic fatigue syndrome
EP  - 24
SN  - 0300-2977
IS  - iss. 1
SP  - 20
JF  - Netherlands Journal of Medicine
VL  - vol. 57
ER  - 
TY  - JOUR
AU  - Soetekouw, P.M.M.B.
AU  - Wevers, R.A.
AU  - Vreken, P.
AU  - Elving, L.D.
AU  - Janssen, A.J.M.
AU  - Veen, Y. van der
AU  - Bleijenberg, G.
AU  - Meer, J.W.M. van der
PY  - 2000
UR  - http://hdl.handle.net/2066/188690
TI  - Normal carnitine levels in patients with chronic fatigue syndrome.
EP  - 24
SN  - 0300-2977
SP  - 20
JF  - Netherlands Journal of Medicine
VL  - vol. 57
PS  - 5 p.
DO  - https://doi.org/10.1016/S0300-2977(00)00030-9
ER  - 
TY  - JOUR
AU  - Buf-Vereijken, P.W.G. du
AU  - Ven, A.J.A.M. van der
AU  - Meis, J.F.G.M.
AU  - Lemmens, J.A.M.
AU  - Meer, J.W.M. van der
PY  - 1999
UR  - http://hdl.handle.net/2066/19787
PB  - Elsevier science bv
TI  - Swelling of hand and forearm caused by Mycobacterium bovis
EP  - 72
SN  - 0300-2977
IS  - iss. 2
SP  - 70
JF  - Netherlands Journal of Medicine
VL  - vol. 54
ER  - 
TY  - JOUR
AU  - Buf-Vereijken, P.W.G. du
AU  - Ven, A.J.A.M. van der
AU  - Meis, J.F.G.M.
AU  - Lemmens, J.A.M.
AU  - Meer, J.W.M. van der
PY  - 1999
UR  - http://hdl.handle.net/2066/19788
PB  - Elsevier science bv
TI  - Reply to letter to the editor of J.H. van Loenhout-Rooyackers [published in the September issue of the Netherlands Journal of Medicine (1999;55 : 163)]
EP  - 249
SN  - 0300-2977
IS  - iss. 5
SP  - 249
JF  - Netherlands Journal of Medicine
VL  - vol. 55
ER  - 
TY  - JOUR
AU  - Ginneken, E.E.M. van
AU  - Meer, J.W.M. van der
AU  - Netten, P.M.
PY  - 1999
UR  - http://hdl.handle.net/2066/19802
PB  - Elsevier science bv
TI  - A man with a mysterious hypogammaglobulinaemia and skin rash
EP  - 162
SN  - 0300-2977
IS  - iss. 4
SP  - 158
JF  - Netherlands Journal of Medicine
VL  - vol. 54
ER  - 
TY  - JOUR
AU  - Buf-Vereijken, P.W.G. du
AU  - Ven, A.J.A.M. van der
AU  - Meis, J.F.G.M.
AU  - Lemmens, J.A.M.
AU  - Meer, J.W.M. van der
PY  - 1999
UR  - http://hdl.handle.net/2066/120787
TI  - Reply to letter to the editor of J.H. van Loenhout-Rooyackers [published in the September issue of The Netherlands Journal of Medicine (1999;55:163)]
EP  - 249
SN  - 0300-2977
SP  - 249
JF  - Netherlands Journal of Medicine
VL  - vol. 55
DO  - https://doi.org/10.1016/S0300-2977(99)00061-3
ER  - 
TY  - JOUR
AU  - Buf-Vereijken, P.W.G. du
AU  - Ven, A.J.A.M. van der
AU  - Meis, J.F.G.M.
AU  - Lemmens, J.A.M.
AU  - Meer, J.W.M. van der
PY  - 1999
UR  - http://hdl.handle.net/2066/120789
TI  - Swelling of hand and forearm caused by Mycobacterium bovis.
EP  - 72
SN  - 0300-2977
SP  - 70
JF  - Netherlands Journal of Medicine
VL  - vol. 54
DO  - https://doi.org/10.1016/S0300-2977(98)00126-0
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
AU  - Broucke-Grauls, C.M.J.E. van den
AU  - Rees-Wortelboer, M.M. van
PY  - 1998
UR  - http://hdl.handle.net/2066/19757
PB  - Elsevier science bv
TI  - The Challenge of Infectious Diseases; the European Perspective - Proceedings of the Symposium Organised Jointly by the Advisory Group for the Health Research Promotion Programme (SGO) and the Dutch Inspectorate for Health Care (IGZ) - 18-19 December 1996, Amsterdam, the Netherlands
EP  - 199
SN  - 0300-2977
IS  - iss. 6
SP  - 199
JF  - Netherlands Journal of Medicine
VL  - vol. 52
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
PY  - 1998
UR  - http://hdl.handle.net/2066/19756
PB  - Elsevier science bv
TI  - How to survive without new antibiotics
EP  - 306
SN  - 0300-2977
IS  - iss. 6
SP  - 303
JF  - Netherlands Journal of Medicine
VL  - vol. 52
ER  - 
TY  - JOUR
AU  - Kleijn, E.M.H.A. de
AU  - Meer, J.W.M. van der
PY  - 1997
UR  - http://hdl.handle.net/2066/15107
TI  - Inquiry into the diagnostic workup of patients with fever of unknown origin
EP  - 74
SN  - 0300-2977
IS  - iss. 2
SP  - 69
JF  - Netherlands Journal of Medicine
VL  - vol. 50
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/15107/inqiinthd.pdf?sequence=2
ER  - 
TY  - JOUR
AU  - Stalenhoef, A.F.H.
AU  - Timmermans, J.
AU  - Meer, J.W.M. van der
PY  - 1996
UR  - http://hdl.handle.net/2066/23250
TI  - Transient bilateral cortical blindness as a presenting symptom of infective endocarditis
EP  - 164
SN  - 0300-2977
IS  - iss. 4
SP  - 163
JF  - Netherlands Journal of Medicine
VL  - vol. 48
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/23250/23250___.PDF?sequence=1
ER  - 
TY  - JOUR
AU  - Kleijn, E.M.H.A. de
AU  - Meer, J.W.M. van der
PY  - 1995
UR  - http://hdl.handle.net/2066/14914
TI  - Fever of unknown origin (FUO) : report on 53 patients in a Dutch university hospital
EP  - 60
SN  - 0300-2977
IS  - iss. 2
SP  - 54
JF  - Netherlands Journal of Medicine
VL  - vol. 47
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14914/4801.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Kleijn, E.M.H.A. de
AU  - Meer, J.W.M. van der
PY  - 1995
UR  - http://hdl.handle.net/2066/22044
TI  - Fever of unknown origin (FUO): report on 53 patients in a Dutch university hospital
EP  - 60
SN  - 0300-2977
SP  - 54
JF  - Netherlands Journal of Medicine
VL  - vol. 47
ER  - 
TY  - JOUR
AU  - Vreden, S.G.S.
AU  - Brenninkmeijer, B.J.
AU  - Meer, J.W.M. van der
PY  - 1992
UR  - http://hdl.handle.net/2066/14876
TI  - Peritoneal tuberculosis in two young immigrants with fever of unknown origin
EP  - 221
SN  - 0300-2977
IS  - iss. 5
SP  - 218
JF  - Netherlands Journal of Medicine
VL  - vol. 41
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14876/4741.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Timmerman, R.J.
AU  - Thompson, J.
AU  - Noordzij, H.M.
AU  - Meer, J.W.M. van der
PY  - 1992
UR  - http://hdl.handle.net/2066/14875
TI  - Psychogenic periodic fever
EP  - 160
SN  - 0300-2977
IS  - iss. 4
SP  - 158
JF  - Netherlands Journal of Medicine
VL  - vol. 41
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14875/4740.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Meer, J.W.M. van der
AU  - Matze-van der Lans, A.
AU  - Mattie, H.
PY  - 1989
UR  - http://hdl.handle.net/2066/14823
TI  - Cefsulodin for the treatment of Pseudomonas infections : a study comparing cefsulodin and ticarcillin
EP  - 242
SN  - 0300-2977
IS  - iss. 6
SP  - 233
JF  - Netherlands Journal of Medicine
VL  - vol. 34
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14823/4497.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Boers, M.
AU  - Peeters, A.J.
AU  - Berkel, M. van
AU  - Graaf, P. de
AU  - Meer, J.W.M. van der
PY  - 1989
UR  - http://hdl.handle.net/2066/14817
TI  - Shigellosis and AIDS : Report of a case and brief review of the literature
EP  - 97
SN  - 0300-2977
SP  - 93
JF  - Netherlands Journal of Medicine
VL  - vol. 34
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14817/4491.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Danner, S.A.
AU  - Lange, J.M.A.
AU  - Meer, J.W.M. van der
AU  - Schipper, M.E.I.
AU  - Goudsmit, J.
AU  - Rietra, P.J.S.M.
AU  - Speelman, J.D.
AU  - Schellekens, P.T.A.
AU  - Haas, D. de
AU  - Kluft, W.
PY  - 1985
UR  - http://hdl.handle.net/2066/14782
TI  - AIDS in the Netherlands, clinical and microbiological data in 36 cases
EP  - 497
SN  - 0300-2977
SP  - 487
JF  - Netherlands Journal of Medicine
VL  - vol. 28
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14782/4450.pdf?sequence=1
ER  - 
TY  - JOUR
AU  - Mosmans-Smits, A.A.H.
AU  - Meer, J.W.M. van der
PY  - 1974
UR  - http://hdl.handle.net/2066/14729
TI  - Amyloid goitre : report of a case and brief review of the literature
EP  - 120
SN  - 0300-2977
IS  - iss. 3
SP  - 115
JF  - Netherlands Journal of Medicine
VL  - vol. 17
L1  - https://repository.ubn.ru.nl/bitstream/handle/2066/14729/4295.pdf?sequence=1
ER  -