The Netherlands Heart Tissue Bank : Strengthening the cardiovascular research infrastructure with an open access Cardiac Tissue Repository.
Publication year
2023Source
Netherlands Heart Journal, 31, 1, (2023), pp. 16-20ISSN
Annotation
01 januari 2023
Publication type
Article / Letter to editor
Display more detailsDisplay less details
Organization
Cardiology
Journal title
Netherlands Heart Journal
Volume
vol. 31
Issue
iss. 1
Page start
p. 16
Page end
p. 20
Subject
Radboudumc 16: Vascular damage Cardiology; Radboud University Medical CenterAbstract
AIM: Cardiac diseases remain a leading cause of cardiovascular disease (CVD) related hospitalisation and mortality. That is why research to improve our understanding of pathophysiological processes underlying cardiac diseases is of great importance. There is a strong need for healthy and diseased human cardiac tissue and related clinical data to accomplish this, since currently used animal and in vitro disease models do not fully grasp the pathophysiological processes observed in humans. This design paper describes the initiative of the Netherlands Heart Tissue Bank (NHTB) that aims to boost CVD-related research by providing an open-access biobank. METHODS: The NHTB, founded in June 2020, is a non-profit biobank that collects and stores biomaterial (including but not limited to myocardial tissue and blood samples) and clinical data of individuals with and without previously known cardiac diseases. All individuals aged ≥ 18 years living in the Netherlands are eligible for inclusion as a potential future donor. The stored samples and clinical data will be available upon request for cardiovascular researchers. CONCLUSION: To improve the availability of cardiac tissue for cardiovascular research, the NHTB will include extensive (cardiac) biosamples, medical images, and clinical data of donors with and without a previously known cardiac disease. As such, the NHTB will function as a translational bridge to boost a wide range of cardiac disease-related fundamental and translational studies.
This item appears in the following Collection(s)
- Academic publications [243907]
- Electronic publications [130616]
- Faculty of Medical Sciences [92803]
- Open Access publications [104924]
Upload full text
Use your RU credentials (u/z-number and password) to log in with SURFconext to upload a file for processing by the repository team.