Research in complex diseases.
Publication year
2002Source
The Lancet (London), 359, 9313, (2002), pp. 1243-5ISSN
Publication type
Article / Letter to editor
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Organization
Rheumatology
Journal title
The Lancet (London)
Volume
vol. 359
Issue
iss. 9313
Page start
p. 1243
Page end
p. 5
Subject
Chronic arthritis: Pathogenesis and treatment; Chronische arthritis: Pathogenese en behandelingAbstract
Many diseases that have a substantial effect on health have a complex pathogenesis. Examples are atherosclerosis, diabetes mellitus, and rheumatoid arthritis. Here, we discuss a hierarchy of goals of research in complex diseases, and introduce a stepwise approach for the development of disease models, paying specific attention to the position of genetic factors and stochastic variables in these models.
This item appears in the following Collection(s)
- Academic publications [245262]
- Faculty of Medical Sciences [93207]
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