An Integrative Literature Review on the Nomenclature and Definition of Dementia at a Young Age
Publication year
2021Source
Journal of Alzheimer's Disease, 83, 4, (2021), pp. 1891-1916ISSN
Publication type
Article / Letter to editor
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Organization
Primary and Community Care
Journal title
Journal of Alzheimer's Disease
Volume
vol. 83
Issue
iss. 4
Page start
p. 1891
Page end
p. 1916
Subject
Radboudumc 18: Healthcare improvement science RIHS: Radboud Institute for Health Sciences; Radboudumc 1: Alzheimer`s disease DCMN: Donders Center for Medical Neuroscience; Primary and Community Care - Radboud University Medical CenterAbstract
BACKGROUND: There has been growing interest in young people living with dementia. Future research requires consensus on the terminology and operational definition of this group. OBJECTIVE: The purpose of this integrative review was to explore and include all operational definitions used to define dementia at a young age. METHODS: On August 14, 2020, the PubMed, Embase, Cinahl, and PsycInfo databases were searched for empirical and theoretical literature using Google. Various terms to describe and define 'dementia' and 'at a young age' were used to collect literature concerning terminology; age-related aspects, including cut-off ages and criteria; and etiologies of dementia at a young age. RESULTS: The search yielded 6,891 empirical and 4,660 theoretical publications, resulting in the inclusion of 89 publications, including 36 publications containing an explicit discussion and 53 publications as confirmation. 'Young-onset dementia' was the most commonly used term of seven identified terms, in the last two decades. The age of 65 years at symptom onset was used most frequently when considering a total of six upper age limits and four criteria to define a cut-off age. Eight lower age limits and an option for subdivision based on age were included. We identified 251 different etiologies and 27 categories of etiologies. CONCLUSION: Despite relative consensus on the term young-onset dementia and an age at symptom onset being used as a cut-off criterion, much is still unclear concerning possible etiologies of dementia at a young age. In the current study, controversies were detected for discussion in an international consensus study.
This item appears in the following Collection(s)
- Academic publications [245262]
- Electronic publications [132642]
- Faculty of Medical Sciences [93207]
- Open Access publications [106238]
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